SCHEMBL2596889

SCHEMBL2596889

C1=C(c2ccccc2)NOc2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3074957 0.87 ALOX5 (0.37)
SCHEMBL3131316 0.81 DRD2 (0.34) LMNA
SCHEMBL29244396 0.75 NISCH (0.33)
SCHEMBL25430258 0.73 ALDH1A1 (0.35) ALDH1A1LMNASMN1; SMN2
SCHEMBL28143327 0.73 NPC1 (0.36) ALDH1A1LMNASMN1; SMN2
SCHEMBL2446923 0.72 KDM4E (0.43) ALDH1A1LMNASMN1; SMN2
SCHEMBL30618039 0.72 RPS6KB2 (0.34) ALDH1A1LMNASMN1; SMN2
SCHEMBL29664451 0.71 NISCH (0.32)
SCHEMBL9368915 0.71 NISCH (0.31)
SCHEMBL31540166 0.70 NISCH (0.44) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240417263-A1 METHOD OF FORMING GRAPHENE FILMS UNIVERSITY OF MASSACHUSETTS 2024-12-19 US claimed
EP-4419481-A2 METHOD OF FORMING GRAPHENE FILMS University Of Massachusetts (US) 2024-08-28 EP claimed
WO-2023132979-A2 METHOD OF FORMING GRAPHENE FILMS UNIVERSITY OF MASSACHUSETTS (US) 2023-07-13 WO claimed
US-20240417263-A1 METHOD OF FORMING GRAPHENE FILMS UNIVERSITY OF MASSACHUSETTS 2024-12-19 US disclosed
EP-4419481-A2 METHOD OF FORMING GRAPHENE FILMS University Of Massachusetts (US) 2024-08-28 EP disclosed
CN-117658939-A Method for synthesizing non-natural beta-amino acid compound by rhodium catalysis 河南大学 2024-03-08 CN disclosed
US-11834424-B2 Compounds useful as chaperone-mediated autophagy modulators ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2023-12-05 US disclosed
EP-4212516-A1 2-PHENYL-6-HALO-QUINOXALINE DERIVATIVES AS CHAPERONE-MEDIATED AUTOPHAGY (CMA) MODULATORS FOR THE TREATMENT OF PARKINGSON'S DISEASE Albert Einstein College of Medicine (US) 2023-07-19 EP disclosed
WO-2023132979-A2 METHOD OF FORMING GRAPHENE FILMS UNIVERSITY OF MASSACHUSETTS (US) 2023-07-13 WO disclosed
US-20210317095-A1 COMPOUNDS USEFUL AS CHAPERONE-MEDIATED AUTOPHAGY MODULATORS ALBERT EINSTEIN COLLEGE OF MEDICINE 2021-10-14 US disclosed
EP-3844155-A1 COMPOUNDS USEFUL AS CHAPERONE-MEDIATED AUTOPHAGY MODULATORS Albert Einstein College of Medicine (US) 2021-07-07 EP disclosed
CN-112714761-A Compounds useful as chaperone mediated modulators of autophagy 阿尔伯爱因斯坦医学院 2021-04-27 CN disclosed
WO-2020046335-A1 COMPOUNDS USEFUL AS CHAPERONE-MEDIATED AUTOPHAGY MODULATORS ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) 2020-03-05 WO disclosed
CN-107083027-A Oxazines resin combination and its manufacture method, prepreg, plywood and hardening thing 新日铁住金化学株式会社 2017-08-22 CN disclosed
EP-2571937-A2 POLYMER COMPOSITIONS CONTAINING OXAZINE-BASED ALKOXYSILANES Dow Corning Corporation (US) 2013-03-27 EP disclosed
US-20130065992-A1 Polymer Compositions Containing Oxazine-Based Alkoxysilanes DOW CORNING CORPORATION (US) 2013-03-14 US disclosed
WO-2011144575-A2 POLYMER COMPOSITIONS CONTAINING OXAZINE-BASED ALKOXYSILANES DOW CORNING CORPORATION (US) 2011-11-24 WO disclosed
EP-2217651-A2 CURABLE COMPOSITIONS CONTAINING ISOCYANATE-BASED TOUGHENERS Henkel AG & Co. KGaA (DE) 2010-08-18 EP disclosed
WO-2009075743-A2 CURABLE COMPOSITIONS CONTAINING ISOCYANATE-BASED TOUGHENERS HENKEL AG & CO. KGAA (DE) 2009-06-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11834424-B2 Compounds useful as chaperone-mediated autophagy modulators SQSTM1, HSPA5, ATG7 ALDH1A1 2631/4885LMNA 3765/4885SMN1; SMN2 2417/4885
US-20210317095-A1 COMPOUNDS USEFUL AS CHAPERONE-MEDIATED AUTOPHAGY MODULATORS SQSTM1, HSPA5, ATG7 ALDH1A1 2631/4885LMNA 3765/4885SMN1; SMN2 2417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.