SCHEMBL24477751

SCHEMBL24477751

COc1cc(SN)ccc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 4/20 0.38
DHFR P00374 1/20 0.38
ALDH1A1 P00352 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
MAPT P10636 2/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
MAPK1 P28482 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CYP3A4 P08684 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
ACHE P22303 1/20 0.35
KMT2A Q03164 2/20 0.35
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34
TUBA1B P68363 1/20 0.34
TUBA4A P68366 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19447572 0.83 ALDH1A1 (0.41) ALDH1A1L3MBTL1MAPTGAAHPGD
SCHEMBL5044907 0.83 CA2 (0.48) DHFRALDH1A1L3MBTL1MAPTMAPK1
SCHEMBL8863279 0.81 L3MBTL1 (0.49) ALDH1A1L3MBTL1MAPTGAAHPGD
SCHEMBL27275492 0.78 POLB (0.45) ALDH1A1L3MBTL1MAPTTAAR1
SCHEMBL11223750 0.75 ALDH1A1 (0.46) ALDH1A1MAPTHPGDMAPK1TDP1
SCHEMBL264325 0.71 MAPT (0.57) DHFRALDH1A1MAPTGAAMAPK1
SCHEMBL92174 0.70 ACHE (0.68) ALDH1A1L3MBTL1MAPTGAAHPGD
SCHEMBL30167567 0.70 ACHE (0.68) ALDH1A1L3MBTL1MAPTGAAHPGD
SCHEMBL9440147 0.70 ALDH1A1 (0.56) DHFRALDH1A1HPGDHSD17B10TDP1
SCHEMBL19203396 0.70 HDAC1 (0.37) ALDH1A1MAPTHSD17B10TDP1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022111621-A1 AMINOHETEROARYL KINASE INHIBITORS ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO., LTD. (CN) 2022-06-02 WO disclosed