Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 4/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | GRK5 | P34947 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4149675 | 0.81 | RET (0.46) | CXCR2CXCR1CA12CA2CA1 | |
| SCHEMBL11090288 | 0.78 | BACE1 (0.36) | CXCR2CXCR1CA12CA2CA1 | |
| SCHEMBL10908088 | 0.78 | LMNA (0.41) | CXCR2CA12CA2CA1CA9 | |
| SCHEMBL10911011 | 0.78 | CA12 (0.33) | CXCR2CA12CA2CA1CA9 | |
| SCHEMBL4129036 | 0.74 | HSD17B10 (0.48) | CXCR2CA2CA1CA9CA7 | |
| SCHEMBL13903712 | 0.74 | KCNA3 (0.38) | CA12CA2CA1CA9NPC1 | |
| SCHEMBL646337 | 0.74 | MAPT (0.34) | NPC1RAB9ASENP8SENP7SENP6 | |
| SCHEMBL350240 | 0.72 | LMNA (0.39) | NPC1ALDH1A1KCNA3 | |
| SCHEMBL31568196 | 0.71 | CXCR2 (0.36) | CXCR2CXCR1 | |
| SCHEMBL2452257 | 0.70 | ALDH1A1 (0.37) | CXCR2CXCR1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143039-A | Benzo five-membered nitrogen ring compound, preparation method and medical application thereof | 山东大学 | 2023-12-01 | — | — | CN | disclosed |
| US-20140135215-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2014-05-15 | — | — | US | disclosed |
| US-8629284-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, LLC (US) | 2014-01-14 | — | — | US | disclosed |
| US-20110218101-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218101-A1 | CHEMICAL COMPOUNDS | CBR3, C3AR1, CCNY | CXCR2 277/4885CXCR1 363/4885CA12 2360/4885 |
| US-20140135215-A1 | CHEMICAL COMPOUNDS | CBR3, CCNY, C3AR1 | CXCR2 289/4885CXCR1 360/4885CA12 2330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.