Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12292150 | 0.78 | RAB9A (0.33) | ALDH1A1HSD17B10NPC1TP53RAB9A | |
| SCHEMBL14397239 | 0.77 | ALDH1A1 (0.33) | ALDH1A1HSD17B10NPC1TP53RAB9A | |
| SCHEMBL13903718 | 0.76 | HTT (0.43) | ALDH1A1HSD17B10NPC1TP53RAB9A | |
| SCHEMBL14397038 | 0.72 | LMNA (0.43) | ALDH1A1HSD17B10NPC1TP53RAB9A | |
| SCHEMBL13903716 | 0.72 | KCNA3 (0.38) | ALDH1A1HSD17B10NPC1SMN1; SMN2HPGD | |
| SCHEMBL13615347 | 0.72 | HPGD (0.39) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL29118472 | 0.72 | RPS6KA2 (0.46) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29118467 | 0.72 | ALOX5 (0.46) | ALDH1A1HSD17B10TP53SMN1; SMN2MEN1 | |
| SCHEMBL29118471 | 0.71 | PTGES (0.55) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL29118494 | 0.71 | ALDH1A1 (0.40) | ALDH1A1HSD17B10SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140135215-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2014-05-15 | — | — | US | disclosed |
| US-8629284-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, LLC (US) | 2014-01-14 | — | — | US | disclosed |
| US-20110218101-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218101-A1 | CHEMICAL COMPOUNDS | CBR3, C3AR1, CCNY | ALDH1A1 2022/4885HSD17B10 1268/4885NPC1 1098/4885 |
| US-20140135215-A1 | CHEMICAL COMPOUNDS | CBR3, CCNY, C3AR1 | ALDH1A1 2199/4885HSD17B10 1410/4885NPC1 1331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.