Benzpiperylon

Benzpiperylon

SCHEMBL24498

CN1CCC(n2[nH]c(-c3ccccc3)c(Cc3ccccc3)c2=O)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 1.00
CYP3A4 P08684 1/20 1.00
CYP2D6 P10635 1/20 1.00
KIF11 P52732 2/20 0.44
DRD2 P14416 4/20 0.42
DRD4 P21917 4/20 0.42
DRD3 P35462 3/20 0.41
PARP1 P09874 1/20 0.41
PARP2 Q9UGN5 1/20 0.41
NR3C1 P04150 7/20 0.41
ADRA1A P35348 1/20 0.39
HRH1 P35367 1/20 0.39
ADRA1B P35368 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
HTR2A P28223 1/20 0.39
CHRM2 P08172 1/20 0.38
CHRM3 P20309 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperylone SCHEMBL25509 0.88 CYP1A2 (0.78) CYP1A2CYP3A4CYP2D6DRD2DRD4
SCHEMBL7546565 0.73 CYP1A2 (0.58) CYP1A2CYP3A4CYP2D6DRD2DRD4
SCHEMBL7546021 0.72 CYP1A2 (0.56) CYP1A2CYP3A4CYP2D6NR3C1
SCHEMBL28480934 0.69 MEN1 (0.56) CYP1A2CYP3A4CYP2D6
SCHEMBL2217280 0.66 NOX4 (0.55) CYP1A2CYP3A4CYP2D6PARP1PARP2
SCHEMBL7544174 0.66 DRD2 (0.58) CYP1A2CYP3A4CYP2D6DRD2DRD4
SCHEMBL28472168 0.62 APAF1 (0.51) CYP1A2CYP3A4CYP2D6
SCHEMBL28300563 0.62 KAT8 (0.47) CYP1A2CYP3A4CYP2D6
SCHEMBL23399055 0.61 ALDH1A1 (0.53) CYP1A2CYP3A4CYP2D6
SCHEMBL12902345 0.61 LSS (0.55) CYP1A2CYP3A4CYP2D6DRD2NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3904 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115538196-B High-color-fastness polyamide 56 fabric and color fixing method thereof 上海凯赛生物技术股份有限公司 2024-02-23 CN claimed
CN-115478443-B Uniform dyeing system and dyeing method for polyamide 56 fabric 上海凯赛生物技术股份有限公司 2024-02-13 CN claimed
US-20240041935-A1 PREVENTION AND TREATMENT OF REPRODUCTIVE FAILURE BY REGENERATIVE CELLS AND ADJUVANTS CREATIVE MEDICAL TECHNOLOGIES, INC. (US) 2024-02-08 US claimed
CN-115538196-A High-color-fastness polyamide 56 fabric and color fixing method thereof 上海凯赛生物技术股份有限公司 2022-12-30 CN claimed
CN-115478443-A Uniform dyeing system and dyeing method for polyamide 56 fabric 上海凯赛生物技术股份有限公司 2022-12-16 CN claimed
EP-3998932-A1 ALKALIZATION OF URINARY BLADDER WALL PRIOR TO TREATMENT WITH INTRAVESICAL HEPARIN AND ALKALINIZED LIDOCAINE TO ENHANCE RELIEF OF BLADDER PAIN SYMPTOMS Parsons, C. Lowell (US) 2022-05-25 EP claimed
CN-114198124-A Construction method for grouting and water plugging of roof fall area of inclined shaft of coal mine 石家庄国盛矿业科技有限公司 2022-03-18 CN claimed
US-11273162-B2 Compositions and methods targeting HCN channels for breathing therapeutics MISSISSIPPI STATE UNIVERSITY (US) 2022-03-15 US claimed
CN-112918052-A Ultraviolet radiation-proof polyethylene fabric and preparation method thereof 江苏厚生新能源科技有限公司 2021-06-08 CN claimed
WO-2021011566-A1 ALKALIZATION OF URINARY BLADDER WALL PRIOR TO TREATMENT WITH INTRAVESICAL HEPARIN AND ALKALINIZED LIDOCAINE TO ENHANCE RELIEF OF BLADDER PAIN SYMPTOMS PARSONS C LOWELL (US) 2021-01-21 WO claimed
EP-0579724-A4 CONFOCAL IMAGING SYSTEM FOR VISIBLE AND ULTRAVIOLET LIGHT. MAYO FOUNDATION (US) 1994-03-23 EP claimed
EP-0579724-A1 CONFOCAL IMAGING SYSTEM FOR VISIBLE AND ULTRAVIOLET LIGHT MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 1994-01-26 EP claimed
US-5260578-A Confocal imaging system for visible and ultraviolet light MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 1993-11-09 US claimed
EP-0296363-B1 CIRCUIT BREAKER WITH SELFPRODUCED FLOW OF EXTINGUISHING GAS AEG Energietechnik GmbH (DE) 1993-04-14 EP claimed
WO-1992018850-A1 CONFOCAL IMAGING SYSTEM FOR VISIBLE AND ULTRAVIOLET LIGHT MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 1992-10-29 WO claimed
EP-0457422-A1 Jet reduction discharge of dye color MILLIKEN RESEARCH CORPORATION (US) 1991-11-21 EP claimed
US-5022891-A Forcing reducing agent interstitial into,pile fabrics MILLIKEN RESEARCH CORPORATION (US) 1991-06-11 US claimed
US-5019166-A Thermal ink jet compositions XEROX CORPORATION (US) 1991-05-28 US claimed
EP-0404494-A1 Thermal ink jet compositions XEROX CORPORATION (US) 1990-12-27 EP claimed
EP-0192196-B1 VEHICLE WHEEL WITH PNEUMATIC TYRES Continental Aktiengesellschaft (DE) 1990-04-25 EP claimed