Piperylone

Piperylone

SCHEMBL25509

CCc1c(-c2ccccc2)[nH]n(C2CCN(C)CC2)c1=O

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.78
CYP3A4 P08684 1/20 0.78
CYP2D6 P10635 1/20 0.78
PARP1 P09874 1/20 0.43
PARP2 Q9UGN5 1/20 0.43
DRD4 P21917 7/20 0.42
DRD2 P14416 6/20 0.42
DRD3 P35462 5/20 0.42
HTR2A P28223 1/20 0.40
CHRM2 P08172 1/20 0.40
CHRM3 P20309 1/20 0.40
CYBB P04839 1/20 0.37
NOX4 Q9NPH5 1/20 0.37
NOX1 Q9Y5S8 1/20 0.37
TLR9 Q9NR96 1/20 0.36
TLR7 Q9NYK1 1/20 0.36
POLB P06746 1/20 0.35
SCN1A P35498 1/20 0.35
SCN2A Q99250 1/20 0.35
SCN3A Q9NY46 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzpiperylon SCHEMBL24498 0.88 CYP1A2 (1.00) CYP1A2CYP3A4CYP2D6PARP1PARP2
SCHEMBL23399055 0.74 ALDH1A1 (0.53) CYP1A2CYP3A4CYP2D6CYBBNOX4
SCHEMBL23403138 0.71 MEN1 (0.46) CYP1A2CYP3A4CYP2D6CYBBNOX4
SCHEMBL23399643 0.70 CYBB (0.44) CYP1A2CYP3A4CYP2D6CYBBNOX4
SCHEMBL23400300 0.69 MEN1 (0.58) CYBBNOX4NOX1POLB
SCHEMBL23403309 0.69 MEN1 (0.57) CYP1A2CYP3A4CYP2D6CYBBNOX4
SCHEMBL23403549 0.68 CYBB (0.42) CYP1A2CYP3A4CYP2D6CYBBNOX4
SCHEMBL23402122 0.68 ALDH1A1 (0.42) CYP1A2CYP3A4CYP2D6CYBBNOX4
SCHEMBL23403203 0.66 ALDH1A1 (0.42) CYP1A2CYP3A4CYP2D6CYBBNOX4
SCHEMBL23400068 0.65 NOX4 (0.48) CYP1A2CYP3A4CYP2D6CYBBNOX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-222680545-U Novel whole frame type diamond wire numerical control stone cutting machine tool 青岛力凯铄石智能科技有限公司 2025-03-28 CN claimed
CN-222376151-U Roof chimney structure 四川绿静环保工程有限公司 2025-01-21 CN claimed
CN-118810041-A IV type hydrogen storage pipe nylon liner hot-melt welding equipment and technology thereof 氢劲科技(江苏)有限公司 2024-10-22 CN claimed
CN-114162583-B Automatic feeding device 浙江环龙机器有限公司 2024-10-15 CN claimed
CN-118493200-A Novel whole frame type diamond wire numerical control stone cutting machine tool 青岛力凯铄石智能科技有限公司 2024-08-16 CN claimed
CN-221431962-U Falling-preventing device system for steel pipe tower 青岛中天斯壮科技有限公司 2024-07-30 CN claimed
CN-115928785-B Wind power stepped assembly type foundation applicable to mountain area and assembly method thereof 重庆大学 2024-07-09 CN claimed
CN-220865182-U Sunshade curtain extension rod structure convenient to assemble and disassemble 江苏德福来汽车部件有限公司 2024-04-30 CN claimed
WO-2024081661-A1 SYSTEMS AND METHODS FOR ELECTROCHEMICAL HYDROGEN LOOPING CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2024-04-18 WO claimed
CN-220785418-U Smooth type stay cord sunshade screen extension rod structure 江苏德福来汽车部件有限公司 2024-04-16 CN claimed
WO-2004082719-A1 DISPERSIBLE PHARMACEUTICAL COMPOSITION FOR TREATMENT OF MASTITIS AND OTIC DISORDERS PHARMACIA CORPORATION (US) 2004-09-30 WO claimed
WO-2004082588-A2 DISPERSIBLE FORMULATION OF AN ANTI-INFLAMMATORY AGENT PHARMACIA CORPORATION (US) 2004-09-30 WO claimed
US-20040156872-A1 Novel nimesulide compositions ELAN PHARMA INTERNATIONAL LTD. 2004-08-12 US claimed
US-20030235617-A1 Pharmaceutical dosage form for mucosal delivery MCNEIL-PPC, INC 2003-12-25 US claimed
US-20030180357-A1 Pharmaceutical tablet MCNEIL-PPC, INC 2003-09-25 US claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
WO-2003066029-A2 PHARMACEUTICAL DOSAGE FORM FOR MUCOSAL DELIVERY PHARMACIA CORPORATION (US) 2003-08-14 WO claimed
WO-2003066030-A2 PHARMACEUTICAL TABLET PHARMACIA CORPORATION (US) 2003-08-14 WO claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040156872-A1 Novel nimesulide compositions NIM1K, NIT2, NCL CYP1A2 3009/4885CYP3A4 1976/4885CYP2D6 1359/4885
US-20030180357-A1 Pharmaceutical tablet GYPA, SORD, SRI CYP1A2 1609/4885CYP3A4 306/4885CYP2D6 252/4885
US-20030235617-A1 Pharmaceutical dosage form for mucosal delivery SI, UGGT1, GYPA CYP1A2 588/4885CYP3A4 67/4885CYP2D6 68/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.