Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5147854 | 0.86 | APOBEC3G (0.48) | APOBEC3GSLC6A4SLC6A2P4HBSLC6A3 | |
| SCHEMBL26505559 | 0.84 | P4HB (0.40) | SLC6A4GABRA1SLC6A2P4HBGABRB2 | |
| SCHEMBL4442278 | 0.82 | APOBEC3G (0.73) | APOBEC3GSLC6A4SLC6A2P4HBSLC6A3 | |
| SCHEMBL30389926 | 0.82 | GABRA1 (0.48) | GABRA1GABRG2GABRB3SLC6A2GABRB2 | |
| SCHEMBL4808650 | 0.82 | GABRA1 (0.48) | GABRA1GABRG2GABRB3SLC6A2GABRB2 | |
| SCHEMBL357956 | 0.78 | GABRA1 (0.58) | APOBEC3GSLC6A4GABRA1GABRG2GABRB3 | |
| SCHEMBL18795670 | 0.78 | SLC6A4 (0.48) | APOBEC3GSLC6A4SLC6A2P4HBSLC6A3 | |
| SCHEMBL30711874 | 0.78 | SLC6A4 (0.48) | APOBEC3GSLC6A4SLC6A2P4HBSLC6A3 | |
| SCHEMBL73812 | 0.77 | APOBEC3G (0.59) | APOBEC3GSLC6A4GABRA1SLC6A2GABRB2 | |
| SCHEMBL18795171 | 0.77 | SLC6A4 (0.47) | APOBEC3GSLC6A4SLC6A2P4HBSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230139111-A1 | DIHYDRONAPHTHYRIDINONE COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | GENFLEET THERAPEUTICS (SHANGHAI) INC. (CN) | 2023-05-04 | — | — | US | disclosed |
| US-20220177462-A1 | SUBSTITUTED HETEROCYCLIC AMIDE COMPOUND AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | GENFLEET THERAPEUTICS (SHANGHAI) INC. (CN) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230139111-A1 | DIHYDRONAPHTHYRIDINONE COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | RIPK1, RIPK4, RIPK3 | APOBEC3G 4655/4885SLC6A4 1329/4885GABRA1 2875/4885 |
| US-20220177462-A1 | SUBSTITUTED HETEROCYCLIC AMIDE COMPOUND AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | RIPK1, RIPK4, RIPK3 | APOBEC3G 4592/4885SLC6A4 3638/4885GABRA1 2703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.