SCHEMBL2449957

SCHEMBL2449957

CC1=NN(c2ccc(C)cc2)C(=O)C1N=Nc1ccc(-c2ccc(N=NC3C(=O)N(c4ccc(C)cc4)N=C3C)c(Cl)c2)cc1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 11/20 0.52
▸ ALDH1A1 P00352 7/20 0.52
▸ NPC1 O15118 6/20 0.52
▸ RAB9A P51151 6/20 0.52
▸ SMN1; SMN2 Q16637 6/20 0.52
▸ MAPK1 P28482 4/20 0.52
▸ TDP1 Q9NUW8 3/20 0.52
▸ LMNA P02545 3/20 0.52
▸ MEN1 O00255 15/20 0.51
▸ KMT2A Q03164 15/20 0.51
▸ XBP1 P17861 1/20 0.48
▸ CTDSP1 Q9GZU7 1/20 0.48
▸ POLB P06746 3/20 0.47
▸ L3MBTL1 Q9Y468 2/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ ATM Q13315 1/20 0.46
▸ CYP1A2 P05177 2/20 0.44
▸ GAA P10253 1/20 0.44
▸ CYP2D6 P10635 1/20 0.43
▸ CYP2C9 P11712 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29356536 1.00 MAPT (0.52) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL9228544 1.00 MAPT (0.52) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL2641824 0.92 MAPT (0.64) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL30078720 0.92 MAPT (0.64) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL29350167 0.92 MAPT (0.64) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL2641828 0.92 MAPT (0.64) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL21611730 0.84 KMT2A (0.52) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL12760847 0.79 MAPT (0.70) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL12760849 0.79 MAPT (0.70) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL12760846 0.79 MAPT (0.70) MAPTALDH1A1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250075051-A1 PROCESS FOR RECYCLING CONTAMINATED POLYMERS ARKEMA FRANCE (FR) 2025-03-06 — — US claimed
EP-4457275-A1 PROCESS FOR RECYCLING CONTAMINATED POLYMERS ARKEMA FRANCE (FR) 2024-11-06 — — EP claimed
WO-2023126441-A1 PROCESS FOR RECYCLING CONTAMINATED POLYMERS ARKEMA FRANCE (FR) 2023-07-06 — — WO claimed
EP-4206267-A1 PROCESS FOR RECYCLING CONTAMINATED POLYMERS ARKEMA FRANCE (FR) 2023-07-05 — — EP claimed
EP-1894406-B1 PRINTING METHOD CONSTANTIA TEICH GMBH (AT) 2011-09-14 — — EP claimed
EP-1894406-A1 PRINTING METHOD TEICH AKTIENGESELLSCHAFT (AT) 2008-03-05 — — EP claimed
WO-2006130890-A1 PRINTING METHOD TEICH AKTIENGESELLSCHAFT (AT) 2006-12-14 — — WO claimed
US-20260022261-A1 SECURITY INK COMPOSITION AND MACHINE-READABLE SECURITY FEATURE DERIVED THEREFROM SICPA HOLDING SA (CH) 2026-01-22 — — US disclosed
US-20250389875-A1 COLORIZED RETROREFLECTIVE MATERIAL AND METHOD OF MANUFACTURE WONG TZE CHING (HK) 2025-12-25 — — US disclosed
US-20250075051-A1 PROCESS FOR RECYCLING CONTAMINATED POLYMERS ARKEMA FRANCE (FR) 2025-03-06 — — US disclosed
EP-4457275-A1 PROCESS FOR RECYCLING CONTAMINATED POLYMERS ARKEMA FRANCE (FR) 2024-11-06 — — EP disclosed
EP-4298160-A1 COLORABLE POLYMERIC COMPOSITIONS EXHIBITING ENHANCED AGING PROPERTIES Dow Global Technologies LLC (US) 2024-01-03 — — EP disclosed
US-20230340239-A1 COLORABLE THERMOPLASTIC POLYMERIC COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-10-26 — — US disclosed
US-20160038628-A1 WETNESS INDICATOR WITH PERMANENT COLORANT THE PROCTER & GAMBLE COMPANY 2016-02-11 — — US disclosed
CN-105143331-A Use of an extrusion processing aid for the production of coloured polyethylene pipes BOREALIS AG 2015-12-09 — — CN disclosed
WO-2014206517-A1 USE OF AN EXTRUSION PROCESSING AID FOR THE PRODUCTION OF COLOURED POLYETHYLENE PIPES BOREALIS AG (AT) 2014-12-31 — — WO disclosed
EP-2818504-A1 Use of an extrusion processing aid for the production of coloured polyethylene pipes Borealis AG (AT) 2014-12-31 — — EP disclosed
EP-1894406-B1 PRINTING METHOD CONSTANTIA TEICH GMBH (AT) 2011-09-14 — — EP disclosed
EP-1894406-A1 PRINTING METHOD TEICH AKTIENGESELLSCHAFT (AT) 2008-03-05 — — EP disclosed
WO-2006130890-A1 PRINTING METHOD TEICH AKTIENGESELLSCHAFT (AT) 2006-12-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022261-A1 SECURITY INK COMPOSITION AND MACHINE-READABLE SECURITY FEATURE DERIVED THEREFROM FGR, LBR, AIFM2 MAPT 434/4885ALDH1A1 4246/4885NPC1 4399/4885
US-20250389875-A1 COLORIZED RETROREFLECTIVE MATERIAL AND METHOD OF MANUFACTURE L1CAM, ALDH1A3, CRY1 MAPT 701/4885ALDH1A1 453/4885NPC1 1673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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