Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22520728 | 0.83 | HRH3 (0.43) | CHRM3FAAHDRD2DRD3POLB | |
| SCHEMBL22318371 | 0.83 | CHRM3 (0.44) | CHRM3FAAHDRD2DRD3POLB | |
| SCHEMBL29313405 | 0.78 | CHRNB2 (0.41) | POLBRXFP1PIK3CDCHRNB2CHRNA3 | |
| SCHEMBL25075232 | 0.77 | FAAH (0.47) | CHRM3FAAHDRD2DRD3POLB | |
| SCHEMBL25075230 | 0.76 | GNAI3 (0.51) | FAAHEPHX2L3MBTL1CHRNB2CHRNA3 | |
| SCHEMBL22302356 | 0.75 | GNAO1 (0.46) | CHRM3DRD2EPHX2HRH1HTR1A | |
| SCHEMBL18513691 | 0.74 | FAAH (0.48) | FAAHEPHX2L3MBTL1CHRNB2CHRNA3 | |
| SCHEMBL23134733 | 0.74 | PIK3CD (0.49) | FAAHL3MBTL1PIK3CD | |
| SCHEMBL24475418 | 0.72 | HRH3 (0.46) | CHRM3DRD2DRD3PIK3CD | |
| SCHEMBL23134546 | 0.72 | CACNA2D1 (0.40) | FAAHPOLBRXFP1EPHX2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120355-A1 | TEAD DEGRADERS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-06-09 | — | — | WO | disclosed |