SCHEMBL25399546

SCHEMBL25399546

CC(=O)c1cc(Br)c2cc(C(F)(F)F)ccn12

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ BAZ2B Q9UIF8 13/20 0.38
▸ BAZ2A Q9UIF9 13/20 0.38
▸ BRD4 O60885 2/20 0.36
▸ BRD9 Q9H8M2 2/20 0.36
▸ BRD2 P25440 1/20 0.36
▸ BRD3 Q15059 1/20 0.36
▸ MAT2A P31153 4/20 0.36
▸ CA2 P00918 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ ALOX15 P16050 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ NOTUM Q6P988 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29547648 0.82 SRD5A2 (0.43) MAPTHPGD
SCHEMBL25400667 0.81 FNTA (0.47) MAT2AMAPTHPGD
SCHEMBL26301906 0.80 BAZ2B (0.49) BAZ2BBAZ2ABRD4BRD9BRD2
SCHEMBL26301942 0.79 BAZ2B (0.51) BAZ2BBAZ2ABRD4BRD9BRD2
SCHEMBL30676989 0.79 MAPT (0.43) ALDH1A1MAPTHPGD
SCHEMBL25400578 0.78 BAZ2B (0.45) BAZ2BBAZ2ABRD4BRD9BRD2
SCHEMBL26301924 0.78 BAZ2B (0.47) BAZ2BBAZ2ABRD4BRD9MAT2A
SCHEMBL29547188 0.78 ALDH1A1 (0.40) ALDH1A1MAPT
SCHEMBL29547156 0.76 L3MBTL1 (0.36) ALDH1A1MAPTHPGDHSD17B10
SCHEMBL26301954 0.75 BAZ2B (0.49) BAZ2BBAZ2ABRD9MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4233864-B1 COMPOSITION COMPRISING AN INDOLIZINE DERIVATIVE AND A CYCLIC DINUCLEOTIDE AS ACTIVE AGENTS UNIV AJOU IND ACADEMIC COOP FOUND (KR) 2025-02-12 — — EP disclosed
US-20230390319-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-12-07 — — US disclosed
EP-4233864-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT Ajou University Industry-Academic Cooperation Foundation (KR) 2023-08-30 — — EP disclosed
WO-2022086260-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT 아주대학교산학협력단 2022-04-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230390319-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT STING1, IRF3, IFNG BAZ2B 4487/4885BAZ2A 4020/4885BRD4 3042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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