Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24512287 | 0.96 | ALDH1A1 (0.36) | ALDH1A1KDM4ELMNAHPGDL3MBTL1 | |
| SCHEMBL24512341 | 0.88 | LMNA (0.33) | ALDH1A1KDM4ELMNAHPGDL3MBTL1 | |
| SCHEMBL24512323 | 0.85 | CNR1 (0.40) | ALDH1A1KDM4ELMNAHPGDL3MBTL1 | |
| SCHEMBL24512303 | 0.82 | DGAT1 (0.41) | — | |
| SCHEMBL24512285 | 0.79 | NPY5R (0.38) | ALDH1A1KDM4ELMNAL3MBTL1HCRTR1 | |
| SCHEMBL24512477 | 0.78 | L3MBTL1 (0.33) | ALDH1A1KDM4ELMNAHPGDL3MBTL1 | |
| SCHEMBL29717098 | 0.77 | POLB (0.49) | ALDH1A1KDM4ELMNAHPGDL3MBTL1 | |
| SCHEMBL24512238 | 0.77 | POLB (0.49) | ALDH1A1KDM4ELMNAHPGDL3MBTL1 | |
| SCHEMBL24512480 | 0.77 | POLB (0.36) | L3MBTL1MAPTNPC1RAB9AGAA | |
| SCHEMBL24512276 | 0.76 | CNR1 (0.39) | ALDH1A1KDM4ELMNAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125989-A1 | COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE, DEGENERATIVE AND METABOLIC DISORDERS | SCRIPPS RESEARCH INSTITUTE, THE (US) | 2022-06-16 | — | — | WO | disclosed |