Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24512337 | 0.91 | NPY5R (0.35) | POLBL3MBTL1NPY5R | |
| SCHEMBL24512285 | 0.88 | NPY5R (0.38) | POLBL3MBTL1NPY5RGAAMAPT | |
| SCHEMBL24512323 | 0.81 | CNR1 (0.40) | POLBL3MBTL1NPC1RAB9ANPY5R | |
| SCHEMBL24512352 | 0.79 | ITGB2 (0.38) | POLBL3MBTL1NPY5R | |
| SCHEMBL24512299 | 0.77 | ALDH1A1 (0.39) | POLBL3MBTL1NPC1RAB9AGAA | |
| SCHEMBL24512287 | 0.75 | ALDH1A1 (0.36) | POLBL3MBTL1NPC1RAB9AGAA | |
| SCHEMBL30899268 | 0.74 | CNR1 (0.43) | POLBL3MBTL1GAAMAPT | |
| SCHEMBL24512244 | 0.74 | CNR1 (0.43) | POLBL3MBTL1GAAMAPT | |
| SCHEMBL24512300 | 0.73 | PIK3C3 (0.37) | — | |
| SCHEMBL24512341 | 0.73 | LMNA (0.33) | POLBL3MBTL1NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125989-A1 | COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE, DEGENERATIVE AND METABOLIC DISORDERS | SCRIPPS RESEARCH INSTITUTE, THE (US) | 2022-06-16 | — | — | WO | disclosed |