Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 6/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.33 |
| ▸ | ITGAL | P20701 | 3/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | PLK4 | O00444 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | PAK4 | O96013 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24512285 | 0.93 | NPY5R (0.38) | NPY5RPIM1POLBL3MBTL1ITGB2 | |
| SCHEMBL24512480 | 0.91 | POLB (0.36) | NPY5RPOLBL3MBTL1 | |
| SCHEMBL24512352 | 0.82 | ITGB2 (0.38) | NPY5RPOLBL3MBTL1ITGB2ICAM1 | |
| SCHEMBL24512323 | 0.80 | CNR1 (0.40) | NPY5RPOLBL3MBTL1HCRTR1 | |
| SCHEMBL24512299 | 0.75 | ALDH1A1 (0.39) | POLBL3MBTL1MAPK1HCRTR1 | |
| SCHEMBL24512122 | 0.74 | CNR2 (0.44) | POLBHCRTR1HCRTR2 | |
| SCHEMBL30899260 | 0.74 | CNR2 (0.44) | POLBHCRTR1HCRTR2 | |
| SCHEMBL4521731 | 0.74 | HTR1A (0.35) | L3MBTL1 | |
| SCHEMBL24512287 | 0.74 | ALDH1A1 (0.36) | POLBL3MBTL1MAPK1HCRTR1 | |
| SCHEMBL24512300 | 0.72 | PIK3C3 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125989-A1 | COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE, DEGENERATIVE AND METABOLIC DISORDERS | SCRIPPS RESEARCH INSTITUTE, THE (US) | 2022-06-16 | — | — | WO | disclosed |