Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 4/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.38 |
| ▸ | ITGAL | P20701 | 4/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 5/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24512285 | 0.86 | NPY5R (0.38) | ITGB2ICAM1ITGALNPY5RCARM1 | |
| SCHEMBL24512337 | 0.82 | NPY5R (0.35) | ITGB2ICAM1ITGALNPY5RCARM1 | |
| SCHEMBL24512480 | 0.79 | POLB (0.36) | NPY5RPOLBL3MBTL1 | |
| SCHEMBL24512323 | 0.79 | CNR1 (0.40) | ACHENPY5RPOLBL3MBTL1 | |
| SCHEMBL29717121 | 0.79 | CNR1 (0.46) | ALOX5APFEN1POLB | |
| SCHEMBL24512148 | 0.79 | CNR1 (0.46) | ALOX5APFEN1POLB | |
| SCHEMBL24512299 | 0.75 | ALDH1A1 (0.39) | POLBL3MBTL1 | |
| SCHEMBL24512287 | 0.73 | ALDH1A1 (0.36) | POLBL3MBTL1 | |
| SCHEMBL24512358 | 0.73 | DRD2 (0.39) | L3MBTL1 | |
| SCHEMBL24512143 | 0.73 | MAP4K1 (0.35) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125989-A1 | COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE, DEGENERATIVE AND METABOLIC DISORDERS | SCRIPPS RESEARCH INSTITUTE, THE (US) | 2022-06-16 | — | — | WO | disclosed |