N-Benzylamphetamine

N-Benzylamphetamine

SCHEMBL2451256

CC(Cc1ccccc1)NCc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 11/20 1.00
LMNA P02545 1/20 0.66
POLB P06746 1/20 0.64
MAPK1 P28482 1/20 0.64
CYP1A2 P05177 1/20 0.63
CYP3A4 P08684 1/20 0.63
CYP2D6 P10635 1/20 0.63
TSHR P16473 1/20 0.63
TAAR1 Q96RJ0 2/20 0.63
SLC18A2 Q05940 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Benzylamphetamine SCHEMBL2798189 1.00 SIGMAR1 (1.00) SIGMAR1LMNAPOLBMAPK1CYP1A2
N-Benzylamphetamine SCHEMBL2795222 1.00 SIGMAR1 (1.00) SIGMAR1LMNAPOLBMAPK1CYP1A2
N-Benzylamphetamine SCHEMBL8085021 0.98 SIGMAR1 (0.96) SIGMAR1LMNAPOLBMAPK1CYP1A2
SCHEMBL606189 0.92 SIGMAR1 (0.85) SIGMAR1LMNAPOLBMAPK1CYP1A2
SCHEMBL608555 0.91 SIGMAR1 (0.82) SIGMAR1LMNAPOLBMAPK1CYP1A2
SCHEMBL8092729 0.91 SIGMAR1 (0.82) SIGMAR1LMNAPOLBMAPK1CYP1A2
SCHEMBL24997843 0.89 SIGMAR1 (0.79) SIGMAR1LMNAPOLBMAPK1CYP1A2
SCHEMBL10005270 0.89 SIGMAR1 (0.79) SIGMAR1LMNAPOLBMAPK1CYP1A2
SCHEMBL3235181 0.89 SIGMAR1 (0.79) SIGMAR1LMNAPOLBMAPK1CYP1A2
SCHEMBL8091283 0.89 SIGMAR1 (0.79) SIGMAR1LMNAPOLBMAPK1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102458543-A Dry powder inhalers 3M INNOVATIVE PROPERTIES CO 2012-05-16 CN claimed
EP-1017358-B1 REDUCTION OF HAIR GROWTH GILLETTE CO (US) 2004-08-11 EP claimed
EP-1017358-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 2000-07-12 EP claimed
US-5939458-A APPLYING AN INHIBITOR OF AMINOACYL-TRNA SYNTHETASE TO THE SKIN GILLETTE COMPANY, THE 1999-08-17 US claimed
WO-1999015136-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 1999-04-01 WO claimed
US-20250213502-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms Pharmapotheca A, Inc. 2025-07-03 US disclosed
US-20250177354-A1 THERAPEUTIC COMBINATIONS, COMPOSITIONS, AND METHODS FOR DESIGNING AND PRODUCING ENTACTOGENIC MINDSTATES MINDSTATE DESIGN LABS INC (US) 2025-06-05 US disclosed
CN-119497589-A Therapeutic combinations, compositions and methods for designing and producing conditions that promote mental well-being 心境设计实验室股份有限公司 2025-02-21 CN disclosed
US-12208068-B2 Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms Pharmapotheca A Inc. (US) 2025-01-28 US disclosed
US-20230321010-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms CHEMAPOTHECA, LLC (US) 2023-10-12 US disclosed
US-11717498-B2 Methods of treatment using amphetamine controlled release, prodrug, and abuse deterrent dosage forms Pharmapotheca A, Inc. (US) 2023-08-08 US disclosed
CN-110668952-B Preparation method of benzphetamine hydrochloride 安徽贝克制药股份有限公司 2023-06-27 CN disclosed
EP-1038522-A2 Anticonvulsant enantiomeric amino acid derivatives Research Corporation Technologies, Inc (US) 2000-09-27 EP disclosed
EP-0938467-A1 PROCESS FOR THE PREPARATION OF OPTICALLY PURE ISOMERS OF FORMOTEROL SEPRACOR, INC. (US) 1999-09-01 EP disclosed
US-5939458-A APPLYING AN INHIBITOR OF AMINOACYL-TRNA SYNTHETASE TO THE SKIN GILLETTE COMPANY, THE 1999-08-17 US disclosed
US-5891696-A CAN BE STORED AT A TEMPERATURE LESS THAN 8.DEGREE. C. FOR AT LEAST TWO WEEKS AND IS ABLE TO OXIDIZE A DRUG AFTER STORAGE PANVERA CORPORATION (US) 1999-04-06 US disclosed
EP-0888289-A1 ANTICONVULSANT ENANTIOMERIC AMINO ACID DERIVATIVES Research Corporation Technologies, Inc (US) 1999-01-07 EP disclosed
US-5773475-A DIPEPTIDES FOR CENTRAL NERVOUS SYSTEM DISORDERS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1998-06-30 US disclosed
WO-1997033861-A1 ANTICONVULSANT ENANTIOMERIC AMINO ACID DERIVATIVES RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1997-09-18 WO disclosed
US-3994974-A BRONCHODILATORS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11717498-B2 Methods of treatment using amphetamine controlled release, prodrug, and abuse deterrent dosage forms SLC6A3, SLC6A2, CES2 SIGMAR1 78/4885LMNA 4850/4885POLB 3555/4885
US-20250177354-A1 THERAPEUTIC COMBINATIONS, COMPOSITIONS, AND METHODS FOR DESIGNING AND PRODUCING ENTACTOGENIC MINDSTATES CNR2, CNR1, HTR6 SIGMAR1 1213/4885LMNA 4701/4885POLB 4724/4885
US-20230321010-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms SLC6A3, CES2, SLC6A2 SIGMAR1 67/4885LMNA 4876/4885POLB 3828/4885
US-12208068-B2 Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms SLC6A3, CES2, SLC6A2 SIGMAR1 67/4885LMNA 4876/4885POLB 3828/4885
US-20250213502-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms SLC6A3, CES2, SLC6A2 SIGMAR1 80/4885LMNA 4869/4885POLB 3877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.