Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.68 |
| ▸ | CA12 | O43570 | 1/20 | 0.68 |
| ▸ | CA2 | P00918 | 1/20 | 0.68 |
| ▸ | CA4 | P22748 | 1/20 | 0.68 |
| ▸ | PPARG | P37231 | 1/20 | 0.68 |
| ▸ | CA7 | P43166 | 1/20 | 0.68 |
| ▸ | IPMK | Q8NFU5 | 1/20 | 0.68 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.68 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.67 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.60 |
| ▸ | TUBB | P07437 | 3/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29647956 | 0.90 | TUBB4A (0.74) | XDHMEN1KMT2ACYP1A1CYP1A2 | |
| SCHEMBL19461012 | 0.90 | TUBB4A (0.74) | XDHMEN1KMT2ACYP1A1CYP1A2 | |
| SCHEMBL16760583 | 0.90 | MKNK2 (0.82) | XDHMEN1KMT2ACYP1A1CYP1A2 | |
| SCHEMBL12590386 | 0.83 | MEN1 (0.69) | XDHMEN1KMT2ACYP1A1CYP1A2 | |
| SCHEMBL31058466 | 0.82 | MKNK2 (0.86) | XDHMKNK2ABCG2NOX4ALOX5 | |
| SCHEMBL29649084 | 0.82 | TUBB4A (0.86) | XDHMEN1KMT2ACYP1A1CYP1A2 | |
| SCHEMBL13560795 | 0.82 | TUBB4A (0.86) | XDHMEN1KMT2ACYP1A1CYP1A2 | |
| Chrysosplenol B SCHEMBL2369883 | 0.82 | ABCG2 (0.78) | XDHMEN1KMT2AMKNK2TUBB4A | |
| Chrysosplenol B SCHEMBL29558792 | 0.82 | ABCG2 (0.78) | XDHMEN1KMT2AMKNK2TUBB4A | |
| SCHEMBL29143220 | 0.82 | MKNK2 (0.86) | XDHMKNK2ABCG2NOX4ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022123573-A1 | COMPOUNDS FOR TREATING EYE DISEASES AND DISORDERS | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) | 2022-06-16 | — | — | WO | disclosed |