Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.78 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.78 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.74 |
| ▸ | TUBB | P07437 | 5/20 | 0.74 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.74 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.74 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.74 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.74 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.74 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.74 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.74 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.74 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.74 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.74 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.74 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.74 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.74 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.71 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.71 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chrysosplenol B SCHEMBL2369883 | 1.00 | ABCG2 (0.78) | ABCG2ABCB1TUBB4ATUBBTUBA3C | |
| SCHEMBL29649084 | 0.93 | TUBB4A (0.86) | ABCG2ABCB1TUBB4ATUBBTUBA3C | |
| SCHEMBL16760583 | 0.93 | MKNK2 (0.82) | ABCG2ABCB1TUBB4ATUBBTUBA3C | |
| SCHEMBL13560795 | 0.93 | TUBB4A (0.86) | ABCG2ABCB1TUBB4ATUBBTUBA3C | |
| Chrysosplenol D SCHEMBL11133546 | 0.93 | ALOX5 (0.83) | ABCG2ABCB1TUBB4ATUBBTUBA3C | |
| Chrysosplenol C SCHEMBL4742072 | 0.93 | ABCG2 (0.73) | ABCG2ABCB1TUBB4ATUBBTUBA3C | |
| Chrysosplenol D SCHEMBL29359614 | 0.93 | ALOX5 (0.83) | ABCG2ABCB1TUBB4ATUBBTUBA3C | |
| Artemetin SCHEMBL2122576 | 0.91 | TUBB4A (0.84) | ABCG2ABCB1TUBB4ATUBBTUBA3C | |
| Artemetin SCHEMBL29416756 | 0.91 | TUBB4A (0.84) | ABCG2ABCB1TUBB4ATUBBTUBA3C | |
| SCHEMBL30082748 | 0.91 | ABCG2 (0.74) | ABCG2ABCB1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114558061-B | Loquat leaf extract and preparation method and application thereof | 浙江大学 | 2023-04-04 | — | — | CN | claimed |
| CN-218646922-U | Detection device for production concentration of chrysosplenetin B | 黑龙江八一农垦大学 | 2023-03-17 | — | — | CN | claimed |
| CN-114558061-A | Loquat leaf extract and preparation method and application thereof | 浙江大学 | 2022-05-31 | — | — | CN | claimed |
| CN-114558061-B | Loquat leaf extract and preparation method and application thereof | 浙江大学 | 2023-04-04 | — | — | CN | disclosed |
| CN-218646922-U | Detection device for production concentration of chrysosplenetin B | 黑龙江八一农垦大学 | 2023-03-17 | — | — | CN | disclosed |
| CN-218646922-U | Detection device for production concentration of chrysosplenetin B | 黑龙江八一农垦大学 | 2023-03-17 | — | — | CN | disclosed |
| CN-114558061-A | Loquat leaf extract and preparation method and application thereof | 浙江大学 | 2022-05-31 | — | — | CN | disclosed |
| WO-2022107054-A1 | INHIBITORS OF THE ADAM17 ENZYME AND COMPOSITIONS COMPRISING THEM FOR THE EFFECTIVE TREATMENT OF COVID-19 | CENTRO DE INVESTIGACIÓN Y DE ESTUDIOS AVANZADOS DEL INSTITUTO POLITÉCNICO NACIONAL (MX) | 2022-05-27 | — | — | WO | disclosed |
| CN-111603496-B | Suspension artemisia rupestris total flavone nano inclusion preparation and preparation method and application thereof | 新疆维吾尔自治区药物研究所 | 2022-04-22 | — | — | CN | disclosed |