Chrysosplenol B

Chrysosplenol B

SCHEMBL2369883

COc1cc(-c2oc3cc(OC)c(OC)c(O)c3c(=O)c2OC)ccc1O

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 2/20 0.78
ABCB1 P08183 1/20 0.78
TUBB4A P04350 5/20 0.74
TUBB P07437 5/20 0.74
TUBA3C P0DPH7 5/20 0.74
TUBA1B P68363 5/20 0.74
TUBA4A P68366 5/20 0.74
TUBB4B P68371 5/20 0.74
TUBB3 Q13509 5/20 0.74
TUBB2A Q13885 5/20 0.74
TUBB8 Q3ZCM7 5/20 0.74
TUBA3E Q6PEY2 5/20 0.74
TUBA1A Q71U36 5/20 0.74
TUBA1C Q9BQE3 5/20 0.74
TUBB6 Q9BUF5 5/20 0.74
TUBB2B Q9BVA1 5/20 0.74
TUBB1 Q9H4B7 5/20 0.74
ALOX5 P09917 2/20 0.71
NR0B1 P51843 1/20 0.71
MKNK2 Q9HBH9 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chrysosplenol B SCHEMBL29558792 1.00 ABCG2 (0.78) ABCG2ABCB1TUBB4ATUBBTUBA3C
SCHEMBL29649084 0.93 TUBB4A (0.86) ABCG2ABCB1TUBB4ATUBBTUBA3C
SCHEMBL16760583 0.93 MKNK2 (0.82) ABCG2ABCB1TUBB4ATUBBTUBA3C
SCHEMBL13560795 0.93 TUBB4A (0.86) ABCG2ABCB1TUBB4ATUBBTUBA3C
Chrysosplenol D SCHEMBL11133546 0.93 ALOX5 (0.83) ABCG2ABCB1TUBB4ATUBBTUBA3C
Chrysosplenol C SCHEMBL4742072 0.93 ABCG2 (0.73) ABCG2ABCB1TUBB4ATUBBTUBA3C
Chrysosplenol D SCHEMBL29359614 0.93 ALOX5 (0.83) ABCG2ABCB1TUBB4ATUBBTUBA3C
Artemetin SCHEMBL2122576 0.91 TUBB4A (0.84) ABCG2ABCB1TUBB4ATUBBTUBA3C
Artemetin SCHEMBL29416756 0.91 TUBB4A (0.84) ABCG2ABCB1TUBB4ATUBBTUBA3C
SCHEMBL30082748 0.91 ABCG2 (0.74) ABCG2ABCB1TUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023219526-A1 MULTITARGET ANTIVIRAL DIETARY SUPPLEMENT PROKIN MILAN (RS) 2023-11-16 WO claimed
CN-218646922-U Detection device for production concentration of chrysosplenetin B 黑龙江八一农垦大学 2023-03-17 CN claimed
CN-111060626-B Artemisia rupestris plant producing area/variety marker based on plant metabonomics and discrimination method 中央民族大学 2022-06-14 CN claimed
CN-114558061-A Loquat leaf extract and preparation method and application thereof 浙江大学 2022-05-31 CN claimed
CN-113855664-A Pharmaceutical composition for inhibiting proliferation and migration of triple negative breast cancer cells and application thereof 成都大学 2021-12-31 CN claimed
WO-2020136240-A1 POLYPHENOL-PEPTIDE CONJUGATES FOR NUCLEAR-TARGETED DELIVERY Universität Wien (AT) 2020-07-02 WO claimed
EP-3673920-A1 POLYPHENOL-PEPTIDE CONJUGATES FOR NUCLEAR-TARGETED DELIVERY Universität Wien (AT) 2020-07-01 EP claimed
CN-108078977-B Application of the chrysosplenetin in treatment osteoporosis 洪郭驹 2019-12-03 CN claimed
CN-109498614-A The new application of chrysosplenetin and qinghaosu trade waste acetone layer 扬州大学 2019-03-22 CN claimed
CN-108078977-A Application of the chrysosplenetin in osteoporosis is treated 洪郭驹 2018-05-29 CN claimed
CN-102633761-B Method for extracting three poly-methoxy-group flavones from industrial production waste UNIV NINGXIA MEDICAL 2014-05-28 CN claimed
CN-102180853-B Anti-enterovirus 71 (EV71) flavonoid compound and application thereof to pharmacy KUNMING INST BOTANY CN ACAD 2013-03-27 CN claimed
CN-102633761-A Method for extracting three poly-methoxy-group flavones from industrial production waste UNIV NINGXIA MEDICAL 2012-08-15 CN claimed
CN-102180853-A Anti-enterovirus 71 (EV71) flavonoid compound and application thereof to pharmacy KUNMING INST BOTANY CN ACAD 2011-09-14 CN claimed
US-12507703-B2 Methods, devices and compositions for preserving human milk THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-12-30 US disclosed
US-20250169516-A1 METHODS, DEVICES AND COMPOSITIONS FOR PRESERVING HUMAN MILK THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-05-29 US disclosed
US-12239142-B2 Methods, devices and compositions for preserving human milk THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-03-04 US disclosed
CN-1465383-A Medical external appliation preparation containing Artemisia apiacea extract 广州市华立健药业有限公司 2004-01-07 CN disclosed
EP-1354914-A1 Polymer composition with a biodegradable polymer and material, extract(s) and/or essential compound(s) from herbs of the Asteraceae family Zikeli, Stefan (AT) 2003-10-22 EP disclosed
EP-0742012-A2 Pharmaceutical composition containing substance inhibiting HSP47 production Kureha Chemical Industry Co., Ltd. (JP) 1996-11-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12507703-B2 Methods, devices and compositions for preserving human milk LPL, CEL, LPO ABCG2 3935/4885ABCB1 4482/4885TUBB4A 2809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.