Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.82 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | CA12 | O43570 | 1/20 | 0.72 |
| ▸ | CA2 | P00918 | 1/20 | 0.72 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | CA4 | P22748 | 1/20 | 0.72 |
| ▸ | PPARG | P37231 | 1/20 | 0.72 |
| ▸ | CA7 | P43166 | 1/20 | 0.72 |
| ▸ | XDH | P47989 | 1/20 | 0.72 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.72 |
| ▸ | IPMK | Q8NFU5 | 1/20 | 0.72 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.72 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.71 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.67 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.67 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.64 |
| ▸ | TUBB | P07437 | 3/20 | 0.64 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chrysosplenol B SCHEMBL2369883 | 0.93 | ABCG2 (0.78) | MKNK2MEN1KMT2AXDHALOX5 | |
| SCHEMBL31058466 | 0.93 | MKNK2 (0.86) | MKNK2XDHALOX5ABCB1ABCG2 | |
| Chrysosplenol B SCHEMBL29558792 | 0.93 | ABCG2 (0.78) | MKNK2MEN1KMT2AXDHALOX5 | |
| SCHEMBL29143220 | 0.93 | MKNK2 (0.86) | MKNK2XDHALOX5ABCB1ABCG2 | |
| SCHEMBL19461012 | 0.93 | TUBB4A (0.74) | MKNK2MEN1KMT2ACA12CA2 | |
| SCHEMBL29647956 | 0.93 | TUBB4A (0.74) | MKNK2MEN1KMT2ACA12CA2 | |
| SCHEMBL38660678 | 0.91 | MKNK2 (0.84) | MKNK2MEN1KMT2ACA12CA2 | |
| SCHEMBL10432667 | 0.90 | MKNK2 (1.00) | MKNK2MEN1KMT2ACYP1A1CYP1A2 | |
| SCHEMBL24514616 | 0.90 | XDH (0.68) | MKNK2MEN1KMT2ACA12CA2 | |
| SCHEMBL1144456 | 0.88 | ABCB1 (0.86) | MKNK2MEN1KMT2ACA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240033246-A1 | COMPOUNDS FOR TREATING EYE DISEASES AND DISORDERS | TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. (IL) | 2024-02-01 | — | — | US | claimed |
| EP-4259173-A1 | COMPOUNDS FOR TREATING EYE DISEASES AND DISORDERS | The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center) (IL) | 2023-10-18 | — | — | EP | claimed |
| US-11752125-B2 | Anti-neuroinflammatory and protective compounds in Achillea fragrantissima | THE STATE OF ISRAEL MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (IL) | 2023-09-12 | — | — | US | claimed |
| WO-2022123573-A1 | COMPOUNDS FOR TREATING EYE DISEASES AND DISORDERS | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) | 2022-06-16 | — | — | WO | claimed |
| EP-3074029-B1 | ANTI-NEUROINFLAMMATORY AND PROTECTIVE COMPOUNDS IN ACHILLEA FRAGRANTISSIMA | THE STATE OF ISRAEL MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT AGRICULTURAL RES ORGANIZATION ARO VO (IL) | 2020-07-29 | — | — | EP | claimed |
| US-20170020842-A1 | ANTI-NEUROINFLAMMATORY AND PROTECTIVE COMPOUNDS IN ACHILLEA FRAGRANTISSIMA | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) | 2017-01-26 | — | — | US | claimed |
| US-20250073292-A1 | PELARGONIUM GRAVEOLENS EXTRACT FOR THE TREATMENT OF TRAUMATIC BRAIN INJURIES | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL R (IL) | 2025-03-06 | — | — | US | disclosed |
| WO-2024154119-A1 | ENRICHED PELARGONIUM GRAVEOLENS EXTRACTS FOR THE TREATMENT OF TRAUMATIC BRAIN INJURIES | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) | 2024-07-25 | — | — | WO | disclosed |
| EP-4380587-A1 | PELARGONIUM GRAVEOLENS EXTRACT FOR THE TREATMENT OF TRAUMATIC BRAIN INJURIES | The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center) (IL) | 2024-06-12 | — | — | EP | disclosed |
| CN-118176008-A | Pelargonium graveolens extract for treating traumatic brain injury | 以色列国家农业与农村发展部农业研究组织（ARO）（Volciti 中心） | 2024-06-11 | — | — | CN | disclosed |
| US-20240033246-A1 | COMPOUNDS FOR TREATING EYE DISEASES AND DISORDERS | TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. (IL) | 2024-02-01 | — | — | US | disclosed |
| US-20240033246-A1 | COMPOUNDS FOR TREATING EYE DISEASES AND DISORDERS | TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. (IL) | 2024-02-01 | — | — | US | disclosed |
| CN-117279653-A | Compounds for the treatment of ocular diseases and disorders | 以色列国家农业和农村发展农业研究组织沃尔坎尼中心 | 2023-12-22 | — | — | CN | disclosed |
| US-20170020842-A1 | ANTI-NEUROINFLAMMATORY AND PROTECTIVE COMPOUNDS IN ACHILLEA FRAGRANTISSIMA | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) | 2017-01-26 | — | — | US | disclosed |
| US-20170020842-A1 | ANTI-NEUROINFLAMMATORY AND PROTECTIVE COMPOUNDS IN ACHILLEA FRAGRANTISSIMA | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) | 2017-01-26 | — | — | US | disclosed |
| CN-106102757-A | Neuritis and protectiveness compound in the Achillea ageratum of pole | 以色列国家农业部、农村发展农业研究组织·沃尔卡尼中心 | 2016-11-09 | — | — | CN | disclosed |
| EP-3074029-A1 | ANTI-NEUROINFLAMMATORY AND PROTECTIVE COMPOUNDS IN ACHILLEA FRAGRANTISSIMA | The State of Israel - Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center) (IL) | 2016-10-05 | — | — | EP | disclosed |
| EP-3074029-A1 | ANTI-NEUROINFLAMMATORY AND PROTECTIVE COMPOUNDS IN ACHILLEA FRAGRANTISSIMA | The State of Israel - Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center) (IL) | 2016-10-05 | — | — | EP | disclosed |
| WO-2015079390-A1 | ANTI-NEUROINFLAMMATORY AND PROTECTIVE COMPOUNDS IN ACHILLEA FRAGRANTISSIMA | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT,AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER). (IL) | 2015-06-04 | — | — | WO | disclosed |
| WO-2015079390-A1 | ANTI-NEUROINFLAMMATORY AND PROTECTIVE COMPOUNDS IN ACHILLEA FRAGRANTISSIMA | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT,AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER). (IL) | 2015-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240033246-A1 | COMPOUNDS FOR TREATING EYE DISEASES AND DISORDERS | TEAD3, TEAD4, TEAD1 | MKNK2 1064/4885MEN1 2709/4885KMT2A 4211/4885 |
| US-20170020842-A1 | ANTI-NEUROINFLAMMATORY AND PROTECTIVE COMPOUNDS IN ACHILLEA FRAGRANTISSIMA | TARDBP, GSTK1, HTT | MKNK2 2372/4885MEN1 3264/4885KMT2A 1189/4885 |
| US-11752125-B2 | Anti-neuroinflammatory and protective compounds in Achillea fragrantissima | TARDBP, GSTK1, HTT | MKNK2 2372/4885MEN1 3264/4885KMT2A 1189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.