Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.69 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.69 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.69 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.69 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 3/20 | 0.67 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | IDE | P14735 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22767679 | 1.00 | F2 (0.69) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL31578516 | 1.00 | F2 (0.69) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL30735826 | 1.00 | F2 (0.69) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL29485943 | 1.00 | F2 (0.69) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL24767163 | 1.00 | F2 (0.69) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL18549029 | 1.00 | F2 (0.69) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL31479957 | 1.00 | F2 (0.69) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL18550538 | 1.00 | F2 (0.69) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL3498955 | 0.99 | F2 (0.67) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL24766888 | 0.99 | F2 (0.67) | F2PRSS1PRSS2PRSS3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260110690-A1 | PROBE AND METHODS FOR IDENTIFYING HOST CELL PROTEIN IMPURITIES | REGENERON PHARMACEUTICALS, INC. | 2026-04-23 | — | — | US | disclosed |
| US-12540945-B2 | Probe and method for identifying host cell protein impurities | REGENERON PHARMACEUTICALS, INC. (US) | 2026-02-03 | — | — | US | disclosed |
| US-12403144-B2 | HECT E3 ligase inhibitors and uses thereof | IFOM —FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE (IT) | 2025-09-02 | — | — | US | disclosed |
| EP-3976185-B1 | HECT E3 LIGASE INHIBITORS AND USES THEREOF | IFOM ST FONDAZIONE DI ONCOLOGIA MOLECOLARE ETS (IT) | 2024-02-14 | — | — | EP | disclosed |
| US-20230184678-A1 | METHODS FOR LOADING AND DATA ACQUISITION | QUANTUM SI INC (US) | 2023-06-15 | — | — | US | disclosed |
| US-20230083288-A1 | PROBE AND METHOD FOR IDENTIFYING HOST CELL PROTEIN IMPURITIES | REGENERON PHARMACEUTICALS, INC. | 2023-03-16 | — | — | US | disclosed |
| US-20220339163-A1 | HECT E3 LIGASE INHIBITORS AND USES THEREOF | IFOM - FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE (IT) | 2022-10-27 | — | — | US | disclosed |
| US-20220187205-A1 | SYSTEMS AND METHODS FOR CHIP REGENERATION | QUANTUM SI INC (US) | 2022-06-16 | — | — | US | disclosed |
| EP-3976185-A1 | HECT E3 LIGASE INHIBITORS AND USES THEREOF | IFOM - Fondazione Istituto FIRC di Oncologia Molecolare (IT) | 2022-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220339163-A1 | HECT E3 LIGASE INHIBITORS AND USES THEREOF | NEDD4, ITCH, UBE3A | F2 4877/4885PRSS1 2721/4885PRSS2 3809/4885 |
| US-12403144-B2 | HECT E3 ligase inhibitors and uses thereof | NEDD4, ITCH, UBE3A | F2 4877/4885PRSS1 2721/4885PRSS2 3809/4885 |
| US-20260110690-A1 | PROBE AND METHODS FOR IDENTIFYING HOST CELL PROTEIN IMPURITIES | BTD, LIPC, LPL | F2 3773/4885PRSS1 1418/4885PRSS2 1093/4885 |
| US-12540945-B2 | Probe and method for identifying host cell protein impurities | BTD, LPL, LYPLA2 | F2 4087/4885PRSS1 1597/4885PRSS2 1637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.