SCHEMBL24517871

SCHEMBL24517871

N=Cc1ccccc1OC(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGES2 Q9H7Z7 1/20 0.40
GAA P10253 2/20 0.38
CCR3 P51677 1/20 0.38
ALDH1A1 P00352 2/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
TRPA1 O75762 2/20 0.36
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
RXRG P48443 1/20 0.35
HCAR1 Q9BXC0 1/20 0.35
LMNA P02545 1/20 0.34
KMT2A Q03164 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HSD11B1 P28845 1/20 0.34
MPL P40238 1/20 0.34
TRPM8 Q7Z2W7 1/20 0.34
TRPV1 Q8NER1 1/20 0.34
GRIN1 Q05586 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9823818 0.83 PTGES2 (0.40) PTGES2GAACCR3ALDH1A1SLC6A2
SCHEMBL4292103 0.83 CCR3 (0.41) PTGES2GAACCR3ALDH1A1TRPA1
SCHEMBL96815 0.79 ALDH1A1 (0.55) PTGES2GAACCR3ALDH1A1RXRA
SCHEMBL11986233 0.79 LMNA (0.34) GAAALDH1A1TRPA1LMNAKMT2A
SCHEMBL1046653 0.79 PTGES2 (0.40) PTGES2GAACCR3ALDH1A1SLC6A2
SCHEMBL4654446 0.77 RXRA (0.47) GAAALDH1A1SLC6A2SLC6A4SLC6A3
SCHEMBL1044650 0.76 PTGES2 (0.45) PTGES2GAACCR3ALDH1A1TRPA1
SCHEMBL1044649 0.76 PTGES2 (0.45) PTGES2GAACCR3ALDH1A1TRPA1
SCHEMBL21222709 0.75 HPGD (0.56) PTGES2GAAALDH1A1LMNAKMT2A
SCHEMBL1095535 0.75 HPGD (0.56) PTGES2GAAALDH1A1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022123530-A1 BORONIC ACID COMPOUND 주식회사 엘지화학 2022-06-16 WO disclosed