Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 10/20 | 0.73 |
| ▸ | RARB | P10826 | 9/20 | 0.73 |
| ▸ | RARG | P13631 | 8/20 | 0.73 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | PGR | P06401 | 1/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.73 |
| ▸ | BLVRB | P30043 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 6/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511656 | 0.95 | RARA (0.77) | RARARARBRARGCYP26A1KMT2A | |
| SCHEMBL9118368 | 0.90 | RARB (0.73) | RARARARBRARGCYP26A1KMT2A | |
| SCHEMBL7152370 | 0.87 | RARB (0.91) | RARARARBRARGCYP26A1KMT2A | |
| Tamibarotene SCHEMBL29373818 | 0.84 | RARB (1.00) | RARARARBRARGCYP26A1KMT2A | |
| Tamibarotene SCHEMBL36207 | 0.84 | RARB (1.00) | RARARARBRARGCYP26A1KMT2A | |
| Tamibarotene SCHEMBL21274122 | 0.84 | RARB (0.83) | RARARARBRARGCYP26A1KMT2A | |
| SCHEMBL30590581 | 0.84 | RARA (1.00) | RARARARBRARGCYP26A1KMT2A | |
| SCHEMBL9118129 | 0.83 | RARA (0.59) | RARARARBRARGCYP26A1KMT2A | |
| Tamibarotene SCHEMBL21055743 | 0.83 | RARB (0.97) | RARARARBRARGCYP26A1KMT2A | |
| SCHEMBL29355626 | 0.82 | RARB (1.00) | RARARARBRARGCYP26A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240059656-A1 | A TAUTOMERIC LIGAND ENABLES BIOMIMETIC C-H HYDROXYLATION WITH MOLECULAR OXYGEN | THE SCRIPPS RESEARCH INSTITUTE | 2024-02-22 | — | — | US | disclosed |
| WO-2022125736-A1 | A TAUTOMERIC LIGAND ENABLES BIOMIMETIC C-H HYDROXYLATION WITH MOLECULAR OXYGEN | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-06-16 | — | — | WO | disclosed |
| WO-2022125736-A1 | A TAUTOMERIC LIGAND ENABLES BIOMIMETIC C-H HYDROXYLATION WITH MOLECULAR OXYGEN | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240059656-A1 | A TAUTOMERIC LIGAND ENABLES BIOMIMETIC C-H HYDROXYLATION WITH MOLECULAR OXYGEN | PAH, OGDH, DOHH | RARA 2478/4885RARB 1820/4885RARG 2349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.