Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24521092 | 0.85 | ADORA2A (0.37) | SMN1; SMN2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL24521040 | 0.83 | MET (0.34) | SMN1; SMN2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL24521217 | 0.83 | HSD17B10 (0.36) | SMN1; SMN2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL24521101 | 0.82 | MEN1 (0.39) | SMN1; SMN2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL24521037 | 0.81 | MET (0.36) | SMN1; SMN2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL24521105 | 0.81 | MEN1 (0.39) | SMN1; SMN2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL24520922 | 0.80 | ALDH1A1 (0.36) | SMN1; SMN2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL24521123 | 0.79 | ALDH1A1 (0.39) | SMN1; SMN2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL24521247 | 0.79 | ALDH1A1 (0.39) | SMN1; SMN2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL24521232 | 0.78 | TDP2 (0.40) | KDM4EALDH1A1MAPTHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015515-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LT Materials Co., Ltd. (KR) | 2022-06-22 | — | — | EP | disclosed |