Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24523725 | 0.80 | IMPDH2 (0.38) | IMPDH2EGLN2MAOAALDH1A1MAPT | |
| SCHEMBL24523744 | 0.80 | AR (0.44) | EGLN2 | |
| SCHEMBL24523731 | 0.79 | IMPDH2 (0.33) | IMPDH2EGLN2MAOAMEN1ALDH1A1 | |
| SCHEMBL24523907 | 0.76 | MAOA (0.40) | IMPDH2MAOAALDH1A1KDM4EMAOB | |
| SCHEMBL24523737 | 0.76 | IMPDH2 (0.35) | IMPDH2MAOAALDH1A1MAPTKDM4E | |
| SCHEMBL24524244 | 0.74 | MAP4K1 (0.37) | IMPDH2ALDH1A1L3MBTL1KDM1ATSHR | |
| SCHEMBL24523748 | 0.74 | MAOA (0.39) | MAOAALDH1A1TDP1KDM4EMAOB | |
| SCHEMBL24523763 | 0.74 | MCL1 (0.43) | CA1CA2 | |
| SCHEMBL24523757 | 0.73 | MAOA (0.38) | CYP11B1CYP11B2MAOAALDH1A1TDP1 | |
| SCHEMBL24523745 | 0.73 | PDCD1 (0.36) | MAOAALDH1A1KDM4EMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129116-A1 | INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |