Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | BRD1 | O95696 | 2/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.32 |
| ▸ | BRPF3 | Q9ULD4 | 2/20 | 0.32 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24523743 | 0.83 | RXFP1 (0.37) | DPP4ENPP3RXFP1CHEK1 | |
| SCHEMBL24523814 | 0.81 | DPP4 (0.32) | DPP4NR3C1PGRNR3C2 | |
| SCHEMBL24523831 | 0.80 | ENPP3 (0.37) | ENPP3CHEK1 | |
| SCHEMBL24523734 | 0.78 | MEN1 (0.40) | DPP4ENPP3 | |
| SCHEMBL23820038 | 0.78 | ROCK2 (0.35) | DPP4 | |
| SCHEMBL24523719 | 0.76 | MEN1 (0.39) | DPP4ENPP3 | |
| SCHEMBL28345512 | 0.75 | KIF11 (0.41) | — | |
| SCHEMBL24523804 | 0.75 | GABRA1 (0.39) | ENPP3CHEK1 | |
| SCHEMBL24523722 | 0.75 | MEN1 (0.38) | DPP4ENPP3 | |
| SCHEMBL24523724 | 0.75 | GABRA1 (0.39) | ENPP3CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129116-A1 | INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |