Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 2/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 5/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.31 |
| ▸ | KDM5A | P29375 | 2/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24523891 | 0.77 | ALDH1A1 (0.39) | IMPDH2IMPDH1KDM4EALDH1A1GAA | |
| SCHEMBL24524261 | 0.74 | PNMT (0.41) | IMPDH2IMPDH1KDM4EALDH1A1GAA | |
| SCHEMBL807524 | 0.73 | TSHR (0.46) | IMPDH2IMPDH1KDM4EALDH1A1GAA | |
| SCHEMBL24523742 | 0.72 | IMPDH2 (0.34) | IMPDH2IMPDH1KDM4EALDH1A1GAA | |
| SCHEMBL24524254 | 0.71 | AR (0.39) | IMPDH2IMPDH1KDM4EALDH1A1GAA | |
| SCHEMBL21871913 | 0.70 | CA1 (0.46) | IMPDH2IMPDH1KDM4EALDH1A1GAA | |
| SCHEMBL24523916 | 0.70 | AR (0.38) | IMPDH2IMPDH1KDM4EALDH1A1GAA | |
| SCHEMBL24523737 | 0.70 | IMPDH2 (0.35) | IMPDH2IMPDH1KDM4EALDH1A1GAA | |
| SCHEMBL26349030 | 0.69 | DYRK1A (0.41) | IMPDH2IMPDH1KDM4EALDH1A1DYRK1A | |
| SCHEMBL24523844 | 0.69 | AR (0.35) | KDM4EALDH1A1PNMTAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129116-A1 | INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |