Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vinyl Ether SCHEMBL2130925 | 1.00 | GPR84 (0.41) | GPR84SPHK1FFAR1LMNACYP3A4 | |
| Vinyl Ether SCHEMBL755749 | 1.00 | GPR84 (0.41) | GPR84SPHK1FFAR1LMNACYP3A4 | |
| Vinyl Ether SCHEMBL25176276 | 0.98 | MAPT (0.38) | GPR84SPHK1FFAR1LMNACYP3A4 | |
| Vinyl Ether SCHEMBL36476 | 0.98 | MAPT (0.38) | GPR84SPHK1FFAR1LMNACYP3A4 | |
| Cyclohexane SCHEMBL6913821 | 0.93 | GPR84 (0.36) | GPR84SPHK1FFAR1LMNACYP3A4 | |
| Vinyl Ether SCHEMBL6025388 | 0.92 | LMNA (0.38) | GPR84SPHK1FFAR1LMNACYP3A4 | |
| Vinyl Ether SCHEMBL2954221 | 0.92 | LMNA (0.38) | GPR84SPHK1FFAR1LMNACYP3A4 | |
| Vinyl Ether SCHEMBL10834012 | 0.92 | CYP3A4 (0.39) | GPR84SPHK1FFAR1LMNACYP3A4 | |
| Vinyl Ether SCHEMBL6025391 | 0.89 | MAPT (0.33) | GPR84SPHK1FFAR1LMNACYP3A4 | |
| Propene SCHEMBL28297517 | 0.85 | GPR84 (0.45) | GPR84SPHK1FFAR1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132248-B1 | ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN | SIKA TECHNOLOGY AG (CH) | 2016-07-13 | — | — | EP | disclosed |
| CN-101687775-B | Aldimines and compositions comprising aldamine | SIKA TECHNOLOGY AG | 2015-05-06 | — | — | CN | disclosed |
| US-8519038-B2 | Aldimines and compositions comprising aldimine | SIKA TECHNOLOGY AG (CH) | 2013-08-27 | — | — | US | disclosed |
| CN-101646707-B | Aldimines with reactive groups comprising active hydrogen | SIKA TECHNOLOGY AG | 2012-10-03 | — | — | CN | disclosed |
| CN-101309898-B | Compounds containing aldimines | SIKA TECHNOLOGY AG | 2012-10-03 | — | — | CN | disclosed |
| US-20120220736-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2012-08-30 | — | — | US | disclosed |
| US-8252859-B2 | Aldimines and compositions comprising aldimine | SIKA TECHNOLOGY AG (CH) | 2012-08-28 | — | — | US | disclosed |
| EP-1934172-B1 | COMPOUNDS CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2011-09-28 | — | — | EP | disclosed |
| US-20100101455-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2010-04-29 | — | — | US | disclosed |
| EP-2178828-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDAMINE | Sika Technology AG (CH) | 2010-04-28 | — | — | EP | disclosed |
| WO-2008116928-A1 | ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN | SIKA TECHNOLOGY AG (CH) | 2008-10-02 | — | — | WO | disclosed |
| EP-1975190-A1 | Aldimines with reactive groups containing active hydrogen | Sika Technology AG (CH) | 2008-10-01 | — | — | EP | disclosed |
| EP-1934169-A1 | ALDIMINES COMPRISING REACTIVE GROUPS CONTAINING ACTIVE HYDROGEN, AND USE THEREOF | Sika Technology AG (CH) | 2008-06-25 | — | — | EP | disclosed |
| EP-1934172-A1 | COMPOUNDS CONTAINING ALDIMINE | Sika Technology AG (CH) | 2008-06-25 | — | — | EP | disclosed |
| EP-1775284-A1 | Compounds comprising aldimine groups | Sika Technology AG (CH) | 2007-04-18 | — | — | EP | disclosed |
| EP-1772447-A1 | Aldimines with reactive groups comprising active hydrogen, and their use | Sika Technology AG (CH) | 2007-04-11 | — | — | EP | disclosed |
| WO-2007036572-A1 | COMPOUNDS CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2007-04-05 | — | — | WO | disclosed |
| WO-2007036571-A1 | ALDIMINES COMPRISING REACTIVE GROUPS CONTAINING ACTIVE HYDROGEN, AND USE THEREOF | SIKA TECHNOLOGY AG (CH) | 2007-04-05 | — | — | WO | disclosed |
| US-5049631-A | Heat resistant | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-09-17 | — | — | US | disclosed |
| US-4299941-A | MODIFIED WITH POLYBASIC ACID POLYALLYL ESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220736-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | ALDOA, ALDH7A1, ALDH3A1 | GPR84 2210/4885SPHK1 3647/4885FFAR1 4013/4885 |
| US-20100101455-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | ALDH7A1, ILK, ALDH3A1 | GPR84 3194/4885SPHK1 4414/4885FFAR1 4533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.