Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 6/20 | 0.63 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194597 | 0.90 | THRB (0.66) | THRBTSHRTGM2ALDH1A1TP53 | |
| SCHEMBL5350028 | 0.87 | THRB (0.62) | THRBTSHRTGM2ALDH1A1TP53 | |
| Benzene SCHEMBL11756759 | 0.86 | TSHR (0.86) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL15941197 | 0.84 | THRB (0.88) | THRBTSHRTGM2LTA4HALDH1A1 | |
| Styrene SCHEMBL6236168 | 0.83 | TSHR (0.63) | THRBTSHRALDH1A1TP53HIF1A | |
| Toluene SCHEMBL27471815 | 0.83 | TSHR (0.63) | THRBTSHRALDH1A1TP53HIF1A | |
| Phthalic Acid SCHEMBL301414 | 0.83 | TSHR (0.63) | THRBTSHRALDH1A1TP53HIF1A | |
| Phthalic Acid SCHEMBL29430009 | 0.83 | TSHR (0.63) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL8861486 | 0.83 | THRB (0.57) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL22129615 | 0.83 | THRB (0.65) | THRBTGM2LTA4HFFAR1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240287232-A1 | BIOSTABLE POLYMER BRUSHES WITH DEFINED VISCOSITY AND OPTICAL PROPERTIES FOR USE IN A NOVEL INTRAOCULAR LENS | ADAPTILENS, LLC | 2024-08-29 | — | — | US | claimed |
| EP-4341324-A1 | BIOSTABLE POLYMER BRUSHES WITH DEFINED VISCOSITY AND OPTICAL PROPERTIES FOR USE IN A NOVEL INTRAOCULAR LENS | Duke University (US) | 2024-03-27 | — | — | EP | claimed |
| WO-2022246198-A1 | BIOSTABLE POLYMER BRUSHES WITH DEFINED VISCOSITY AND OPTICAL PROPERTIES FOR USE IN A NOVEL INTRAOCULAR LENS | DUKE UNIVERSITY (US) | 2022-11-24 | — | — | WO | claimed |
| US-20250277078-A1 | TRI-ARM STAR BOTTLEBRUSH POLYMER WITH DEFINED VISCOSITY AND OPTICAL PROPERTIES FOR USE IN A NOVEL INTRAOCULAR LENS | DUKE UNIVERSITY (US) | 2025-09-04 | — | — | US | disclosed |
| US-20240287232-A1 | BIOSTABLE POLYMER BRUSHES WITH DEFINED VISCOSITY AND OPTICAL PROPERTIES FOR USE IN A NOVEL INTRAOCULAR LENS | ADAPTILENS, LLC | 2024-08-29 | — | — | US | disclosed |
| EP-4341324-A1 | BIOSTABLE POLYMER BRUSHES WITH DEFINED VISCOSITY AND OPTICAL PROPERTIES FOR USE IN A NOVEL INTRAOCULAR LENS | Duke University (US) | 2024-03-27 | — | — | EP | disclosed |
| WO-2022246198-A1 | BIOSTABLE POLYMER BRUSHES WITH DEFINED VISCOSITY AND OPTICAL PROPERTIES FOR USE IN A NOVEL INTRAOCULAR LENS | DUKE UNIVERSITY (US) | 2022-11-24 | — | — | WO | disclosed |
| US-11165045-B2 | Organic light-emitting device and method of manufacturing the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-11-02 | — | — | US | disclosed |
| EP-3225635-B1 | MODIFIED BUTADIENE POLYMER AND MODIFYING AGENT USEFUL IN PRODUCTION OF SAME | LG CHEMICAL LTD (KR) | 2019-09-04 | — | — | EP | disclosed |
| US-10184012-B2 | Modified butadiene-based polymer and modifier useful for preparing the same | LG CHEM, LTD. (KR) | 2019-01-22 | — | — | US | disclosed |
| EP-3352706-A1 | INTRAOCULAR LENS | Physiol (BE) | 2018-08-01 | — | — | EP | disclosed |
| US-20020165206-A1 | Inhibitory or blocking agents of molecular generating and/or inducing functions | KOYAMA SHOZO (JP) | 2002-11-07 | — | — | US | disclosed |
| US-20020151615-A1 | RADIATION-CURABLE COATING COMPOSITION | DSM IP ASSETS B.V. (NL) | 2002-10-17 | — | — | US | disclosed |
| EP-1232196-A1 | RADIATION-CURABLE COATING COMPOSITION | DSM N.V. (NL) | 2002-08-21 | — | — | EP | disclosed |
| US-6346551-B1 | ANTIBACTERIAL, ANTIFUNGAL, ANTIVIRAL, BACTERICIDAL AND/OR STERILIZATION AGENTS, ANTICANCER DRUGS, BLOOD COAGULATION AND FIBRINOLYSIS INHIBITORS AND/OR BLOCKING AGENTS, INHIBITORY AND/OR BLOCKING AGENTS OF ANTIGEN-ANTIBODY REACTIONS | KOYAMA SHOZO (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1177227-A1 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | SURGIDEV CORPORATION (US) | 2002-02-06 | — | — | EP | disclosed |
| US-6281319-B1 | HYDRATABLE POLYMER | SURGIDEV CORPORATION | 2001-08-28 | — | — | US | disclosed |
| WO-2001027181-A1 | RADIATION-CURABLE COATING COMPOSITION | DSM N.V. (NL) | 2001-04-19 | — | — | WO | disclosed |
| WO-2000061646-A1 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | SURGIDEV CORPORATION (US) | 2000-10-19 | — | — | WO | disclosed |
| EP-0780122-A1 | DEPRESSANT OF FUNCTIONS DEVELOPED BY MOLECULE | Koyama, Shozo (JP) | 1997-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10184012-B2 | Modified butadiene-based polymer and modifier useful for preparing the same | BICRA, SMCHD1, PHB1 | THRB 4545/4885TSHR 4785/4885TGM2 3528/4885 |
| US-20020165206-A1 | Inhibitory or blocking agents of molecular generating and/or inducing functions | CD69, TFPI, SERPINE1 | THRB 1803/4885TSHR 1025/4885TGM2 2796/4885 |
| US-20240287232-A1 | BIOSTABLE POLYMER BRUSHES WITH DEFINED VISCOSITY AND OPTICAL PROPERTIES FOR USE IN A NOVEL INTRAOCULAR LENS | HBZ, FHIT, BZW2 | THRB 2306/4885TSHR 1746/4885TGM2 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.