Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EIF4E | P06730 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29560681 | 0.75 | KDM4E (0.43) | RAB9ANPC1ALDH1A1MAPTGAA | |
| SCHEMBL21813838 | 0.75 | KDM4E (0.43) | RAB9ANPC1ALDH1A1MAPTGAA | |
| SCHEMBL29559836 | 0.74 | NQO2 (0.39) | RAB9ANPC1ALDH1A1HPGDMAPT | |
| SCHEMBL22866803 | 0.71 | LMNA (0.37) | RAB9ANPC1LMNAALDH1A1HPGD | |
| SCHEMBL29661920 | 0.71 | LMNA (0.37) | RAB9ANPC1LMNAALDH1A1HPGD | |
| SCHEMBL22866806 | 0.70 | PSMD14 (0.42) | ALDH1A1HPGDMAPTGAAKDM4E | |
| SCHEMBL29560196 | 0.70 | PSMD14 (0.42) | ALDH1A1HPGDMAPTGAAKDM4E | |
| SCHEMBL30690085 | 0.70 | PLA2G2A (0.83) | RAB9ANPC1LMNAPLA2G2AALDH1A1 | |
| SCHEMBL22939596 | 0.69 | NPC1 (0.56) | RAB9ANPC1LMNAPLA2G2AALDH1A1 | |
| SCHEMBL21447016 | 0.68 | TDP1 (0.51) | RAB9ANPC1ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133303-A1 | COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE, DEGENERATIVE AND METABOLIC DISORDERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-06-23 | — | — | WO | disclosed |