Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10054004 | 0.89 | CYP2D6 (0.33) | CYP19A1NOS3NOS1NOS2NPC1 | |
| SCHEMBL37724 | 0.72 | ACHE (0.35) | CYP19A1TBXAS1ACHEHSP90AA1CCR1 | |
| SCHEMBL23555959 | 0.71 | CYP11B2 (0.44) | CYP19A1NPC1 | |
| SCHEMBL23556041 | 0.70 | CYP11B2 (0.43) | CYP19A1NPC1 | |
| SCHEMBL9059690 | 0.69 | MMP2 (0.31) | CYP19A1L3MBTL1 | |
| SCHEMBL26030241 | 0.69 | PDK2 (0.32) | — | |
| SCHEMBL15888966 | 0.68 | TSHR (0.44) | CYP19A1 | |
| SCHEMBL828264 | 0.68 | ALDH1A1 (0.39) | CYP19A1TBXAS1ACHE | |
| SCHEMBL10054044 | 0.68 | NOS3 (0.32) | NOS3NOS1NOS2NPC1HSP90AA1 | |
| SCHEMBL6397093 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133265-A1 | STEROIDAL COMPOUND DERIVATIVES AS THERAPEUTIC AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORTED (US) | 2022-06-23 | — | — | WO | disclosed |