Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.43 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1648005 | 1.00 | CA2 (0.50) | CA2CYP19A1ATMKDM4EALDH1A1 | |
| SCHEMBL27873824 | 1.00 | CA2 (0.50) | CA2CYP19A1ATMKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL27962953 | 0.98 | CYP19A1 (0.49) | CA2CYP19A1ATMKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL5035634 | 0.98 | CYP19A1 (0.49) | CA2CYP19A1ATMKDM4EALDH1A1 | |
| SCHEMBL9162474 | 0.86 | TAAR1 (0.54) | ALDH1A1TSHRCYP3A4LMNAMAPK1 | |
| SCHEMBL16974124 | 0.83 | CA2 (0.53) | CA2CYP19A1ATMKDM4EALDH1A1 | |
| SCHEMBL25846300 | 0.83 | ALDH1A1 (0.45) | CYP19A1KDM4EALDH1A1PPARGPPARD | |
| SCHEMBL11258047 | 0.81 | CA2 (0.59) | CA2CYP19A1ATMKDM4EALDH1A1 | |
| SCHEMBL31432907 | 0.81 | CYP19A1 (0.50) | CA2CYP19A1ATMKDM4EALDH1A1 | |
| SCHEMBL31149052 | 0.81 | CYP19A1 (0.50) | CA2CYP19A1ATMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702383-B2 | Methods for producing D-α-methyldopa | IMMUNOMOLECULAR THERAPEUTICS, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-20220194893-A1 | Methods for Producing D-alpha-Methyldopa | IMMUNOMOLECULAR THERAPEUTICS, INC. | 2022-06-23 | — | — | US | disclosed |
| CN-104628600-B | A kind of preparation method of (S)-methyldopa midbody compound | 上海医药工业研究院 | 2016-08-24 | — | — | CN | disclosed |
| CN-104628600-A | Preparation method for (S)-methyldopa intermediate compound | SHANGHAI INST PHARM INDUSTRY | 2015-05-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702383-B2 | Methods for producing D-α-methyldopa | AMPD2, AMPD3, AMPD1 | CA2 4308/4885CYP19A1 141/4885ATM 3023/4885 |
| US-20220194893-A1 | Methods for Producing D-alpha-Methyldopa | DBH, AMPD2, DRD2 | CA2 3975/4885CYP19A1 148/4885ATM 3620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.