SCHEMBL2453973

SCHEMBL2453973

C=C(C)CCOC(=O)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.62
TDP1 Q9NUW8 2/20 0.61
TSHR P16473 2/20 0.50
MAPK1 P28482 1/20 0.50
HIF1A Q16665 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A3 Q01959 1/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
ALDH1A1 P00352 1/20 0.49
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
F2 P00734 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2708103 0.91 TSHR (0.52) LMNATDP1TSHRMAPK1SLC6A2
SCHEMBL21986662 0.90 TDP1 (0.68) LMNATDP1TSHRMAPK1HIF1A
SCHEMBL21986682 0.88 TDP1 (0.71) LMNATDP1TSHRMAPK1HIF1A
SCHEMBL7557139 0.85 LMNA (0.67) LMNATDP1TSHRMAPK1HIF1A
SCHEMBL17231745 0.84 ESR1 (0.64) LMNATDP1TSHRMAPK1SLC6A2
SCHEMBL28716635 0.84 ALDH1A1 (0.61) LMNATDP1TSHRMAPK1HIF1A
SCHEMBL13360685 0.83 LMNA (0.56) LMNATDP1TSHRMAPK1HIF1A
SCHEMBL4951087 0.83 L3MBTL1 (0.47) LMNATDP1TSHRKMT2ASMN1; SMN2
SCHEMBL13283577 0.83 MAPT (0.53) LMNATDP1MAPK1SMN1; SMN2ALDH1A1
SCHEMBL28777752 0.82 LMNA (0.62) LMNATDP1TSHRMAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250212873-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-03 US claimed
EP-4482306-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-01 EP claimed
WO-2023192424-A1 VOLATILE HD AC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS CROSS-REFERENCE TO RELATED APPLICATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-05 WO claimed
US-3954842-A FROM OLEFINS AND FORMALDEHYDE IN A SATURATED ESTER SOLVENT PHILLIPS PETROLEUM COMPANY (US) 1976-05-04 US claimed
US-20250212873-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-03 US disclosed
EP-4482306-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-01 EP disclosed
WO-2023192424-A1 VOLATILE HD AC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS CROSS-REFERENCE TO RELATED APPLICATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-05 WO disclosed
US-11655360-B2 Gas-barrier resin composition and use thereof SHOWA DENKO K.K. (JP) 2023-05-23 US disclosed
CN-110799600-B Gas barrier resin composition and use thereof 昭和电工株式会社 2022-06-21 CN disclosed
US-20210275998-A1 CATALYSTS, METHODS OF MAKING, AND METHODS OF HYDROFLUORINATION UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) 2021-09-09 US disclosed
US-20210147669-A1 GAS-BARRIER RESIN COMPOSITION AND USE THEREOF SHOWA DENKO K.K. (JP) 2021-05-20 US disclosed
US-10702858-B2 Methods of hydrofluorination UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) 2020-07-07 US disclosed
US-20100204184-A1 Phosphonates useful as modulators of T-gamma-9-delta-2 activity LABORATOIRES MAYOLY SPINDLER (FR) 2010-08-12 US disclosed
US-20100204184-A1 Phosphonates useful as modulators of T-gamma-9-delta-2 activity LABORATOIRES MAYOLY SPINDLER (FR) 2010-08-12 US disclosed
US-20100204184-A1 Phosphonates useful as modulators of T-gamma-9-delta-2 activity LABORATOIRES MAYOLY SPINDLER (FR) 2010-08-12 US disclosed
US-20060241087-A1 Phosphonates useful as modulators of t $g(g)9$g(d)2 lymphocyte activity MONTERO JEAN-LOUIS 2006-10-26 US disclosed
EP-0302406-B1 Novel alternate copolymers KURARAY CO (JP) 1994-10-05 EP disclosed
US-4814425-A ISOPENTENYL COMPOUNDS KURARAY CO., LTD. (JP) 1989-03-21 US disclosed
EP-0302406-A2 Novel alternate copolymers KURARAY CO., LTD. (JP) 1989-02-08 EP disclosed
US-3954842-A FROM OLEFINS AND FORMALDEHYDE IN A SATURATED ESTER SOLVENT PHILLIPS PETROLEUM COMPANY (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204184-A1 Phosphonates useful as modulators of T-gamma-9-delta-2 activity CD4, PRKCD, PRKCZ LMNA 2695/4885TDP1 2298/4885TSHR 1416/4885
US-20210275998-A1 CATALYSTS, METHODS OF MAKING, AND METHODS OF HYDROFLUORINATION FLI1, EWSR1, KRAS LMNA 1502/4885TDP1 1149/4885TSHR 4796/4885
US-10702858-B2 Methods of hydrofluorination FLI1, INF2, EWSR1 LMNA 1692/4885TDP1 1596/4885TSHR 4722/4885
US-20060241087-A1 Phosphonates useful as modulators of t $g(g)9$g(d)2 lymphocyte activity CD4, GNG2, PLCG2 LMNA 3304/4885TDP1 2214/4885TSHR 2353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.