SCHEMBL24548251

SCHEMBL24548251

N#Cc1ccc(Nc2cccc(CCc3ccccc3)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 10/20 0.48
ABCB1 P08183 6/20 0.48
MAOB P27338 3/20 0.47
MAOA P21397 2/20 0.47
ABCC1 P33527 2/20 0.46
ALDH1A1 P00352 3/20 0.46
MEN1 O00255 2/20 0.46
MAPT P10636 2/20 0.46
KMT2A Q03164 2/20 0.46
AR P10275 1/20 0.46
KDM4E B2RXH2 1/20 0.45
GAA P10253 1/20 0.45
LMNA P02545 2/20 0.43
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
GSK3B P49841 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL510240 0.81 ALDH1A1 (0.62) ABCG2ABCB1MAOBMAOAABCC1
SCHEMBL9481712 0.81 ALDH1A1 (0.62) ABCG2ABCB1MAOBMAOAABCC1
Diphenylamine SCHEMBL9561950 0.79 MAPT (0.58) MAOBMAOAALDH1A1MEN1MAPT
SCHEMBL15158542 0.79 ABCG2 (0.59) ABCG2ABCB1ABCC1ALDH1A1MEN1
SCHEMBL16481440 0.78 ALDH1A1 (0.62) ABCG2ABCB1ABCC1ALDH1A1MEN1
SCHEMBL6960019 0.77 MAOB (0.66) ABCG2ABCB1MAOBMAOAMAPT
SCHEMBL6156438 0.76 ALDH1A1 (0.61) ABCG2ALDH1A1MEN1MAPTKMT2A
SCHEMBL6950852 0.76 TSHR (0.52) MAOBMAOAALDH1A1MEN1KMT2A
SCHEMBL6932079 0.75 ALDH1A1 (0.65) MAOBMAOAALDH1A1MEN1MAPT
Diphenylamine SCHEMBL9782686 0.75 HSD17B10 (0.67) MAOBMAOAALDH1A1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220195199-A1 COLORED FUNCTIONALIZED [2,2] PARACYCLOPHANE AND COLORED CHEMICAL FILM NATIONAL TAIWAN UNIVERSITY (TW) 2022-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220195199-A1 COLORED FUNCTIONALIZED [2,2] PARACYCLOPHANE AND COLORED CHEMICAL FILM CYP1A2, CYP1A1, CYP1B1 ABCG2 1049/4885ABCB1 367/4885MAOB 209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.