Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | MLYCD | O95822 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26763421 | 1.00 | GRM5 (0.54) | GRM5MLYCDEPHX2HPGDSGABRA5 | |
| SCHEMBL5429490 | 0.81 | HDAC1 (0.66) | GRM5MLYCDHPGDSGABRA5XDH | |
| SCHEMBL13164714 | 0.81 | GRM5 (0.56) | GRM5MLYCDHPGDSXDHALDH1A1 | |
| SCHEMBL19983089 | 0.80 | BAZ2B (0.56) | GRM5EPHX2KCNQ3KCNQ2 | |
| SCHEMBL22924505 | 0.80 | GRM5 (0.51) | GRM5MLYCDHPGDSGABRA5AURKA | |
| SCHEMBL853202 | 0.79 | HDAC1 (0.64) | GRM5MLYCDEPHX2HPGDSGABRA5 | |
| SCHEMBL21401430 | 0.79 | GRM5 (0.54) | GRM5MLYCDHPGDSGABRA5XDH | |
| SCHEMBL6870509 | 0.79 | LMNA (0.60) | GRM5ALDH1A1LMNA | |
| SCHEMBL16495982 | 0.79 | RXFP1 (0.61) | GRM5GABRA5 | |
| SCHEMBL13702140 | 0.78 | ERN1 (0.55) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220194930-A1 | Matrix Metalloproteinase Inhibitors and Imaging Agents, And Methods Using Same | UNIV YALE (US) | 2022-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220194930-A1 | Matrix Metalloproteinase Inhibitors and Imaging Agents, And Methods Using Same | MMP3, MMP1, MMP10 | GRM5 3464/4885MLYCD 3397/4885EPHX2 1177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.