Phosphocholine

Phosphocholine

SCHEMBL2456735

C=C(C)C(=O)O.C[N+](C)(C)CCOP(=O)([O-])O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.42
ADRA1A P35348 2/20 0.41
LMNA P02545 2/20 0.41
ESR1 P03372 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
CDC25A P30304 1/20 0.41
AGTR1 P30556 1/20 0.41
AKT1 P31749 1/20 0.41
KCNH2 Q12809 1/20 0.41
CHRM5 P08912 4/20 0.40
CHRM1 P11229 4/20 0.40
CHRM3 P20309 4/20 0.40
CHRM2 P08172 3/20 0.40
CHRM4 P08173 3/20 0.40
HTR1A P08908 2/20 0.40
CHRNB2 P17787 2/20 0.40
CHRNA7 P36544 2/20 0.40
CHRNA4 P43681 2/20 0.40
PGR P06401 1/20 0.40
TBXA2R P21731 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphocholine SCHEMBL19386100 0.89 CHRM5 (0.42) SMN1; SMN2ADRA1ALMNAESR1ADORA3
Phosphocholine SCHEMBL8773459 0.88 SMN1; SMN2 (0.47) SMN1; SMN2ADRA1ALMNAESR1ADORA3
Phosphocholine SCHEMBL1802772 0.86 CHRM5 (0.42) SMN1; SMN2ADRA1ALMNAESR1ADORA3
Phosphocholine SCHEMBL9613934 0.86 LMNA (0.52) SMN1; SMN2ADRA1ALMNAESR1ADORA3
Phosphocholine SCHEMBL8011 0.86 LMNA (0.52) SMN1; SMN2ADRA1ALMNAESR1ADORA3
Phosphocholine SCHEMBL14742786 0.86 LMNA (0.52) SMN1; SMN2ADRA1ALMNAESR1ADORA3
Phosphocholine SCHEMBL6156988 0.84 SMN1; SMN2 (0.47) SMN1; SMN2ADRA1ALMNAESR1ADORA3
Phosphocholine SCHEMBL8584618 0.84 LMNA (0.50) SMN1; SMN2ADRA1ALMNAESR1ADORA3
Phosphocholine SCHEMBL18662890 0.84 SMN1; SMN2 (0.50) SMN1; SMN2ADRA1ALMNAESR1ADORA3
Phosphocholine SCHEMBL5143800 0.84 SMN1; SMN2 (0.50) SMN1; SMN2ADRA1ALMNAESR1ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260072020-A1 PRINTABLE MOLECULE-SELECTIVE CORE-SHELL NANOPARTICLES FOR WEARABLE AND IMPLANTABLE SENSING CALIFORNIA INST OF TECHN (US) 2026-03-12 US claimed
US-20250188521-A1 NUCLEIC ACID DELIVERY SCAFFOLDS Singular Genomics Systems, Inc. 2025-06-12 US claimed
CN-119529204-A Triblock expansion viscosity-increasing carbon dioxide channeling profile control agent and preparation method thereof 中国石油大学(华东) 2025-02-28 CN claimed
US-12220550-B2 Transdermal delivery device, methods of using and making the same BUDDHIST TZU CHI MEDICAL FOUNDATION (TW) 2025-02-11 US claimed
US-20240167089-A1 NANOARRAYS AND METHODS OF USE THEREOF FIRST-CITIZENS BANK & TRUST COMPANY 2024-05-23 US claimed
US-20240167087-A1 MULTI-DIMENSIONAL POLYMER SCAFFOLDS FOR NUCLEIC ACID ANALYSES FIRST-CITIZENS BANK & TRUST COMPANY 2024-05-23 US claimed
EP-4371653-A1 FABRICATION OF FILTRATION MEMBRANES Trustees of Tufts College (US) 2024-05-22 EP claimed
CN-114957721-B Zwitterionic hydrogel and preparation method and application thereof 四川大学 2024-04-26 CN claimed
CN-117757127-A Preparation method of polyethylene material with biocompatibility and application of polyethylene material in medical field 华东理工大学 2024-03-26 CN claimed
US-11884977-B2 Nanoarrays and methods of use thereof Singular Genomics Systems, Inc. (US) 2024-01-30 US claimed
EP-3074440-A1 MIKTO-ARM BRANCHED POLYMERS Commonwealth Scientific & Industrial Research Organisation ( C.S.I.R.O. ) (AU) 2016-10-05 EP claimed
WO-2016109621-A1 ZWITTERIONIC COPOLYMERS FOR FOULING RESISTANT FILTRATION MEMBRANES TUFTS UNIVERSITY (US) 2016-07-07 WO claimed
US-20150164853-A1 PROSTACYCLIN COMPOSITIONS FOR REGULATION OF FRACTURE REPAIR AND BONE FORMATION MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH 2015-06-18 US claimed
WO-2015077831-A1 MIKTO-ARM BRANCHED POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2015-06-04 WO claimed
WO-2014190398-A1 INHIBITION OF AMYLOID FIBRIL FORMATION THE UNIVERSITY OF MELBOURNE (AU) 2014-12-04 WO claimed
US-20130276407-A1 Packaging Solutions SANTARUS, INC. 2013-10-24 US claimed
US-20120290075-A1 MODIFICATION OF BIOABSORBABLE STENT TO REDUCE THROMBOGENECITY ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2012-11-15 US claimed
US-20110251677-A1 Coating Designs For The Tailored Release Of Dual Drugs From Polymeric Coatings ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2011-10-13 US claimed
WO-2009055306-A2 COATING DESIGNS FOR THE TAILORED RELEASE OF DUAL DRUGS FROM POLYMERIC COATINGS ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2009-04-30 WO claimed
US-20090104247-A1 Coating Designs For The Tailored Release Of Dual Drugs From Polymeric Coatings ABBOTT CARDIOVASCULAR SYSTEMS INC. 2009-04-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150164853-A1 PROSTACYCLIN COMPOSITIONS FOR REGULATION OF FRACTURE REPAIR AND BONE FORMATION PTGIR, PTGIS, PTGS1 SMN1; SMN2 4839/4885ADRA1A 1217/4885LMNA 2695/4885
US-20260072020-A1 PRINTABLE MOLECULE-SELECTIVE CORE-SHELL NANOPARTICLES FOR WEARABLE AND IMPLANTABLE SENSING MIF, HMOX2, HMOX1 SMN1; SMN2 2725/4885ADRA1A 1924/4885LMNA 4003/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.