Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 11/20 | 0.31 |
| ▸ | CIT | O14578 | 3/20 | 0.31 |
| ▸ | GAK | O14976 | 3/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.31 |
| ▸ | BMP2K | Q9NSY1 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | PRKG2 | Q13237 | 2/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21398692 | 0.77 | USP2 (0.39) | SMARCA2AAK1CITGAKMKNK1 | |
| SCHEMBL11994360 | 0.72 | SMARCA2 (0.38) | SMARCA2AAK1CITGAKMKNK1 | |
| SCHEMBL19853215 | 0.72 | SMARCA2 (0.35) | SMARCA2ADRB2AAK1CITGAK | |
| SCHEMBL24568256 | 0.70 | ALDH1A1 (0.47) | — | |
| SCHEMBL17981895 | 0.70 | AAK1 (0.36) | SMARCA2AAK1CITGAKMKNK1 | |
| SCHEMBL17000211 | 0.70 | SMARCA2 (0.36) | SMARCA2AAK1CITGAKMKNK1 | |
| SCHEMBL27406023 | 0.70 | SMARCA2 (0.36) | SMARCA2AAK1CITGAKMKNK1 | |
| SCHEMBL17897224 | 0.67 | RXRA (0.36) | SMARCA2AAK1CITGAKMKNK1 | |
| SCHEMBL19003575 | 0.67 | — | — | |
| SCHEMBL24568388 | 0.67 | P2RX7 (0.37) | KDM4EADRB2LRRK2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140428-A2 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |