Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 7/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.41 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.41 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.41 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10585602 | 0.80 | KIF11 (0.43) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL4298574 | 0.78 | MGLL (0.50) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL29229878 | 0.77 | KIF11 (0.41) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL10702685 | 0.77 | ALDH1A1 (0.37) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL63468 | 0.76 | ALDH1A1 (0.67) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL6821296 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TSHR | |
| SCHEMBL10700885 | 0.74 | AKR1C3 (0.43) | KIF11 | |
| SCHEMBL5535744 | 0.74 | CES2 (0.41) | ALDH1A1TSHRCES2 | |
| SCHEMBL2056226 | 0.74 | SLC2A1 (0.58) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL13367596 | 0.74 | KIF11 (0.50) | ALDH1A1TSHRKIF11CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2542531-A1 | PROCESS FOR SYNTHESIS OF FIPRONIL | Gharda, Keki Hormusji (IN) | 2013-01-09 | — | — | EP | claimed |
| WO-2011107998-A1 | PROCESS FOR SYNTHESIS OF FIPRONIL | GHARDA KEKI HORMUSJI (IN) | 2011-09-09 | — | — | WO | claimed |
| US-10202352-B2 | Process for preparation of aminopyrazole | GHARDA CHEMICALS LIMITED (IN) | 2019-02-12 | — | — | US | disclosed |
| US-20180282284-A1 | PROCESS FOR PREPARATION OF AMINOPYRAZOLE | GHARDA CHEMICALS LIMITED (IN) | 2018-10-04 | — | — | US | disclosed |
| WO-2017060787-A1 | PROCESS FOR PREPARATION OF AMINOPYRAZOLE | GHARDA CHEMICALS LIMITED (IN) | 2017-04-13 | — | — | WO | disclosed |
| CN-102093295-A | Synthesis method of insecticide Fipronil | JIANGSU CHANGQING AGRICULTURAL AND CHEMICAL CO LTD | 2011-06-15 | — | — | CN | disclosed |
| CN-100519510-C | Process for the preparation of a synthetic intermediate for pesticides | BAYER CROPSCIENCE SA (FR) | 2009-07-29 | — | — | CN | disclosed |
| CN-1705632-A | Novel Preparation Method of Pesticide Synthesis Intermediate | BAYER CROPSCIENCE SA (FR) | 2005-12-07 | — | — | CN | disclosed |
| EP-1259476-B1 | CHLORINATION OF AN ANILINE IN ORTHO IN A HYDROFLUORIC MEDIUM | RHODIA CHIMIE SA (FR) | 2005-10-05 | — | — | EP | disclosed |
| US-6747175-B2 | EXCHANGING A CHLORINE ATOM AND A FLUORINE ATOM IN A BENZYL POSITION; RING CHLORINATION | RHODIA CHIMIE (FR) | 2004-06-08 | — | — | US | disclosed |
| US-20030130542-A1 | Chlorination of an aniline in a hydrofluoric medium | RHODIA CHIMIE (FR) | 2003-07-10 | — | — | US | disclosed |
| EP-1259476-A1 | CHLORINATION OF AN ANILINE IN ORTHO IN A HYDROFLUORIC MEDIUM | RHODIA CHIMIE (FR) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001064623-A1 | CHLORINATION OF AN ANILINE IN ORTHO IN A HYDROFLUORIC MEDIUM | RHODIA CHIMIE (FR) | 2001-09-07 | — | — | WO | disclosed |
| US-5616810-A | DEALKYLATION BY REACTING AN N-ALKYL OF N,N-DIALKYL ANILINE WITH AMMONIA OR A PRIMARY OR SECONDARY AMINE USING A PYRIDINE SALT CATALYST | RHONE-POULENC CHIMIE (FR) | 1997-04-01 | — | — | US | disclosed |
| US-5401882-A | Reaction of halobenzenes with dialkyl amide to form dialkyl anilines, dealkylation | RHONE-POULENC CHIMIE (FR) | 1995-03-28 | — | — | US | disclosed |
| EP-0385809-A1 | Pesticidal 3-cyano-5-alkoxy-1-arylpyrazoles | RHONE-POULENC AGROCHIMIE (FR) | 1990-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10202352-B2 | Process for preparation of aminopyrazole | CYP3A4, CYP3A5, CYP4F3 | ALDH1A1 1320/4885TSHR 2954/4885KIF11 1703/4885 |
| US-20180282284-A1 | PROCESS FOR PREPARATION OF AMINOPYRAZOLE | CYP3A4, CYP3A5, CYP4F3 | ALDH1A1 1320/4885TSHR 2954/4885KIF11 1703/4885 |
| US-20030130542-A1 | Chlorination of an aniline in a hydrofluoric medium | PEX3, PHF13, ATL3 | ALDH1A1 1409/4885TSHR 2492/4885KIF11 1102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.