Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 11/20 | 0.54 |
| ▸ | QPCTL | Q9NXS2 | 4/20 | 0.54 |
| ▸ | PRKCI | P41743 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2455532 | 0.86 | QPCT (0.40) | QPCTQPCTLPRKCIKDM4ENPC1 | |
| SCHEMBL8634290 | 0.81 | QPCT (0.68) | QPCTQPCTLPRKCIKDM4ENPC1 | |
| SCHEMBL2462345 | 0.77 | QPCT (0.68) | QPCTQPCTLPRKCIKDM4ENPC1 | |
| SCHEMBL991449 | 0.76 | QPCT (0.58) | QPCTQPCTLPRKCIKDM4ESMN1; SMN2 | |
| SCHEMBL23227763 | 0.75 | QPCT (0.60) | QPCTQPCTLPRKCIKDM4ENPC1 | |
| SCHEMBL29804755 | 0.75 | QPCT (0.60) | QPCTQPCTLPRKCIKDM4ENPC1 | |
| SCHEMBL2474515 | 0.74 | QPCT (0.60) | QPCTQPCTLPRKCIKDM4ENPC1 | |
| SCHEMBL22418756 | 0.74 | QPCT (0.64) | QPCTQPCTLPRKCIKDM4ENPC1 | |
| SCHEMBL28190281 | 0.74 | QPCT (0.64) | QPCTQPCTLPRKCIKDM4ENPC1 | |
| SCHEMBL23207344 | 0.73 | QPCT (0.55) | QPCTQPCTLPRKCIKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237633-A1 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-09-29 | — | — | US | disclosed |
| WO-2010068287-A2 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | ANGION BIOMEDICA CORP. (US) | 2010-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237633-A1 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | HGF, HDGF, MET | QPCT 3492/4885QPCTL 4285/4885PRKCI 1031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.