Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | ATP4A | P20648 | 1/20 | 0.45 |
| ▸ | ATP4B | P51164 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24577342 | 0.87 | KDM4E (0.53) | LMNAHSP90AA1HSP90AB1KDM4EL3MBTL1 | |
| SCHEMBL25540965 | 0.84 | LMNA (0.58) | LMNAATP4AATP4BHSP90AA1HSP90AB1 | |
| SCHEMBL30582646 | 0.84 | LMNA (0.58) | LMNAATP4AATP4BHSP90AA1HSP90AB1 | |
| SCHEMBL13833017 | 0.84 | MEN1 (0.55) | LMNAKDM4EDPP4L3MBTL1POLB | |
| SCHEMBL38655879 | 0.83 | HSP90AA1 (0.62) | LMNAATP4AATP4BHSP90AA1HSP90AB1 | |
| SCHEMBL18731952 | 0.81 | MEN1 (0.56) | LMNAKDM4EDPP4L3MBTL1POLB | |
| SCHEMBL18731948 | 0.81 | MEN1 (0.56) | LMNAKDM4EDPP4L3MBTL1POLB | |
| SCHEMBL21058449 | 0.81 | HSP90AA1 (0.46) | LMNAHSP90AA1HSP90AB1KDM4EL3MBTL1 | |
| SCHEMBL602372 | 0.81 | HSP90AA1 (0.46) | LMNAATP4AATP4BHSP90AA1HSP90AB1 | |
| SCHEMBL423874 | 0.80 | KDM4E (0.66) | LMNAATP4AATP4BHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10227528-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2019-03-12 | — | — | US | disclosed |
| EP-2935276-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-11-01 | — | — | EP | disclosed |
| US-20150337197-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
| US-20150337197-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
| US-20150340627-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
| US-20150340627-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
| WO-2014106524-A2 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2014-07-10 | — | — | WO | disclosed |
| WO-2014094963-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2014-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150340627-A1 | MATERIALS FOR ELECTRONIC DEVICES | ESR1, EPX, SDHB | LMNA 3804/4885ATP4A 3130/4885ATP4B 2235/4885 |
| US-10227528-B2 | Materials for organic electroluminescent devices | OR10J3, EPCAM, L1CAM | LMNA 3281/4885ATP4A 3350/4885ATP4B 2447/4885 |
| US-20150337197-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | OR10J3, EML4, L1CAM | LMNA 3041/4885ATP4A 3697/4885ATP4B 2720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.