Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL834652 | 0.83 | RAB9A (0.50) | KMT2AMEN1CYP1A2RAB9ALMNA | |
| SCHEMBL27686848 | 0.80 | KMT2A (0.49) | KEAP1KMT2AMEN1CYP1A2SMN1; SMN2 | |
| SCHEMBL7759208 | 0.78 | KMT2A (0.47) | KEAP1KMT2AMEN1CYP1A2SMN1; SMN2 | |
| SCHEMBL14186806 | 0.78 | KEAP1 (0.42) | KEAP1KMT2AMEN1CYP1A2SMN1; SMN2 | |
| SCHEMBL24577694 | 0.77 | KMT2A (0.64) | KEAP1KMT2AMEN1CYP1A2SMN1; SMN2 | |
| SCHEMBL922692 | 0.77 | KMT2A (0.69) | KMT2AMEN1CYP1A2SMN1; SMN2POLB | |
| SCHEMBL4698700 | 0.77 | IKBKB (0.46) | KEAP1KMT2AMEN1CYP1A2POLB | |
| SCHEMBL2937630 | 0.77 | KMT2A (0.46) | KEAP1KMT2AMEN1CYP1A2POLB | |
| SCHEMBL6306700 | 0.75 | KMT2A (0.45) | KEAP1KMT2AMEN1CYP1A2SMN1; SMN2 | |
| SCHEMBL23079439 | 0.74 | STING1 (0.50) | KMT2AMEN1CYP1A2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718607-B2 | Atypical coupling method for the preparation of 1,2-di(thiophen-2-yl)ethene-1,2-diol compounds via a Cu(II) catalyst | QATAR UNIVERSITY (QA) | 2023-08-08 | — | — | US | disclosed |
| US-11718607-B2 | Atypical coupling method for the preparation of 1,2-di(thiophen-2-yl)ethene-1,2-diol compounds via a Cu(II) catalyst | QATAR UNIVERSITY (QA) | 2023-08-08 | — | — | US | disclosed |
| US-20220204487-A1 | ATYPICAL COUPLING METHOD FOR THE PREPARATION OF 1,2-DI(THIOPHEN-2-YL)ETHENE-1,2-DIOL COMPOUNDS VIA A CU(II) CATALYST | QATAR UNIVERSITY (QA) | 2022-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718607-B2 | Atypical coupling method for the preparation of 1,2-di(thiophen-2-yl)ethene-1,2-diol compounds via a Cu(II) catalyst | AP2A2, AP2A1, DNM2 | KEAP1 935/4885KMT2A 2598/4885MEN1 947/4885 |
| US-20220204487-A1 | ATYPICAL COUPLING METHOD FOR THE PREPARATION OF 1,2-DI(THIOPHEN-2-YL)ETHENE-1,2-DIOL COMPOUNDS VIA A CU(II) CATALYST | AP2A2, AP2A1, DNM2 | KEAP1 935/4885KMT2A 2598/4885MEN1 947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.