Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27686848 | 0.85 | KMT2A (0.49) | RAB9AKMT2AMEN1CYP1A2 | |
| SCHEMBL7759208 | 0.83 | KMT2A (0.47) | RAB9AKMT2AMEN1CYP1A2 | |
| SCHEMBL24577693 | 0.83 | KEAP1 (0.50) | RAB9AKMT2ADHODHLMNAMEN1 | |
| SCHEMBL922692 | 0.82 | KMT2A (0.69) | KMT2ALMNAMEN1CYP1A2 | |
| SCHEMBL2937630 | 0.82 | KMT2A (0.46) | KMT2ALMNAMEN1CYP1A2 | |
| SCHEMBL4698700 | 0.82 | IKBKB (0.46) | KMT2ACA1CA2MEN1CYP1A2 | |
| SCHEMBL1162160 | 0.80 | RAB9A (0.48) | RAB9AL3MBTL1ESR2KMT2APTPRC | |
| SCHEMBL6306700 | 0.80 | KMT2A (0.45) | KMT2AMEN1CYP1A2 | |
| SCHEMBL11659943 | 0.79 | RAB9A (0.54) | RAB9AL3MBTL1ESR2KMT2APTPRC | |
| SCHEMBL20505372 | 0.79 | RAB9A (0.47) | RAB9AL3MBTL1ESR2KMT2APTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297168-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-11-20 | — | — | US | claimed |
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-15 | — | — | US | claimed |
| US-12011444-B2 | N-substituted indole derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-18 | — | — | US | disclosed |
| CN-115515958-B | Novel sulfonamide (Menin-MLL) interaction inhibitor, preparation method and medical application thereof | 成都苑东生物制药股份有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116693533-A | Five-membered heteroaromatic ring type gin-MLL interaction inhibitor, preparation method and medical application thereof | 成都硕德药业有限公司 | 2023-09-05 | — | — | CN | disclosed |
| US-11667667-B2 | Steroid derivative FXR agonist | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-06-06 | — | — | US | disclosed |
| US-11667667-B2 | Steroid derivative FXR agonist | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-06-06 | — | — | US | disclosed |
| EP-3600312-B1 | PIPERIDINYL- AND PIPERAZINYL-SUBSTITUTED HETEROAROMATIC CARBOXAMIDES AS MODULATORS OF GPR6 | TAKEDA PHARMACEUTICALS CO (JP) | 2023-05-17 | — | — | EP | disclosed |
| CN-110520127-B | Piperidinyl-substituted and piperazinyl-substituted heteroaromatic carboxamides as modulators of GPR6 | 武田药品工业株式会社 | 2023-05-16 | — | — | CN | disclosed |
| WO-2023074408-A1 | THIOPHENE COMPOUND, METHOD FOR SYNTHESIZING SAME, AND COMPOSITION CONTAINING SAID THIOPHENE COMPOUND | 四国化成工業株式会社 | 2023-05-04 | — | — | WO | disclosed |
| US-20230065745-A1 | PIPERIDINE-2,6-DIONE DERIVATIVES WHICH BIND TO CEREBLON, AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S.A. (PL) | 2023-03-02 | — | — | US | disclosed |
| EP-0053603-B1 | 1-(3-(2-HYDROXY-3-ALKYLAMINOPROPOXY)-2-THIENYL)-3-PHENYL-1 PROPANONES AND THEIR ACID ADDITION SALTS, AND PROCESS FOR THEIR PREPARATION | Laevosan-Gesellschaft m.b.H. & Co KG (AT) | 1985-04-03 | — | — | EP | disclosed |
| EP-0117780-A1 | Process for the preparation of perhalogenoalkylthio ethers | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-09-05 | — | — | EP | disclosed |
| US-4461903-A | Antibiotic nodusmicin derivatives | THE UPJOHN COMPANY (US) | 1984-07-24 | — | — | US | disclosed |
| US-4448970-A | ANTIBIOTICS, BACTERICIDES | THE UPJOHN COMPANY (US) | 1984-05-15 | — | — | US | disclosed |
| US-4363922-A | Esters of antibiotic nodusmicin | THE UPJOHN COMPANY (US) | 1982-12-14 | — | — | US | disclosed |
| US-4360683-A | Antibiotic nodusmicin derivatives | THE UPJOHN COMPANY (US) | 1982-11-23 | — | — | US | disclosed |
| US-4352819-A | ANTIARRHYTHMIA AGENTS | LAEVOSAN-GESELLSCHAFT MBH & CO. KG (AT) | 1982-10-05 | — | — | US | disclosed |
| US-4351769-A | Antibiotic composition of matter | THE UPJOHN COMPANY (US) | 1982-09-28 | — | — | US | disclosed |
| EP-0053603-A1 | 1-(3-(2-Hydroxy-3-alkylaminopropoxy)-2-thienyl)-3-phenyl-1 propanones and their acid addition salts, and process for their preparation | Laevosan-Gesellschaft m.b.H. & Co KG (AT) | 1982-06-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12011444-B2 | N-substituted indole derivatives as PGE2 receptor modulators | PTGER1, PTGER4, PTGER2 | RAB9A 3072/4885L3MBTL1 4704/4885ESR2 143/4885 |
| US-11667667-B2 | Steroid derivative FXR agonist | NR1H4, SLC10A1, FXR1 | RAB9A 2902/4885L3MBTL1 4741/4885ESR2 216/4885 |
| US-20230065745-A1 | PIPERIDINE-2,6-DIONE DERIVATIVES WHICH BIND TO CEREBLON, AND METHODS OF USE THEREOF | CRBN, CDR2, FABP7 | RAB9A 3890/4885L3MBTL1 4821/4885ESR2 1035/4885 |
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, CKMT1A; CKMT1B, CYB5R3 | RAB9A 4235/4885L3MBTL1 4673/4885ESR2 2607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.