SCHEMBL2457775

SCHEMBL2457775

O=C1C2=C(c3cccc4ccccc34)N(Cc3ccccc3)C(=O)C2=C(c2cccc3ccccc23)N1Cc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.56
KMT2A Q03164 4/20 0.49
MAPT P10636 3/20 0.49
MEN1 O00255 3/20 0.49
CYP1B1 Q16678 1/20 0.49
RGS12 O14924 1/20 0.49
USP2 O75604 1/20 0.49
LMNA P02545 1/20 0.49
HTT P42858 1/20 0.49
RECQL P46063 1/20 0.49
SIRT2 Q8IXJ6 1/20 0.49
CASP3 P42574 1/20 0.47
ALDH1A1 P00352 3/20 0.46
ALDH2 P05091 1/20 0.46
CHRM1 P11229 1/20 0.46
CES1 P23141 1/20 0.46
ALDH3A1 P30838 1/20 0.46
F2 P00734 1/20 0.44
PLG P00747 1/20 0.44
ELANE P08246 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2457896 0.89 GSK3B (0.47) NPSR1MAPTLMNAHTTALDH1A1
SCHEMBL2457538 0.85 NPSR1 (0.42) NPSR1KMT2AMAPTMEN1CYP1B1
SCHEMBL6153269 0.83 GSK3B (0.45) NPSR1MAPTLMNAHTTALDH1A1
SCHEMBL2457833 0.81 CYP1B1 (0.51) NPSR1KMT2AMAPTMEN1CYP1B1
SCHEMBL5073360 0.75 NR1H2 (0.57) NPSR1KMT2AMEN1SIRT2CASP3
SCHEMBL10086968 0.73 P2RX4 (0.43) MAPTLMNAHTTSIRT2GSK3B
SCHEMBL6153208 0.72 RGS4 (0.47) KMT2AMAPTMEN1LMNASIRT2
SCHEMBL2457350 0.72 RGS4 (0.41) KMT2AMEN1LMNAALDH1A1GSK3B
SCHEMBL6152442 0.72 POLB (0.47) KMT2AMAPTMEN1USP2LMNA
SCHEMBL5594225 0.72 NPSR1 (1.00) NPSR1KMT2AMAPTMEN1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1341403-B1 LUMINESCENT ELEMENT MATERIAL AND LUMINESCENT ELEMENT COMPRISING THE SAME TORAY INDUSTRIES (JP) 2016-05-11 EP disclosed
EP-2365735-B1 Luminescent element material and luminescent element comprising the same TORAY INDUSTRIES (JP) 2013-08-28 EP disclosed
EP-2365735-A2 Luminescent element material and luminescent element comprising the same TORAY INDUSTRIES INC. (JP) 2011-09-14 EP disclosed
US-7318966-B2 Luminescent element material and luminescent element comprising the same TORAY INDUSTRIES, INC. (JP) 2008-01-15 US disclosed
US-20030168970-A1 Luminescent element material and luminescent element comprising the same TORAY INDUSTRIES, INC. (JP) 2003-09-11 US disclosed
EP-1341403-A1 LUMINESCENT ELEMENT MATERIAL AND LUMINESCENT ELEMENT COMPRISING THE SAME Toray Industries, Inc. (JP) 2003-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030168970-A1 Luminescent element material and luminescent element comprising the same SAAL1, EBPL, CSNK1A1L NPSR1 1111/4885KMT2A 3458/4885MAPT 4865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.