Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CLTC | Q00610 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MDH2 | P40926 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2457896 | 0.94 | GSK3B (0.47) | GSK3BCLTCNPSR1P2RX4CA12 | |
| SCHEMBL10086968 | 0.87 | P2RX4 (0.43) | GSK3BCLTCP2RX4CA12CA9 | |
| SCHEMBL2457350 | 0.83 | RGS4 (0.41) | GSK3BCLTCP2RX4CA12CA9 | |
| SCHEMBL2457775 | 0.83 | NPSR1 (0.56) | GSK3BCLTCNPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL6153208 | 0.82 | RGS4 (0.47) | P2RX4CA12CA9MDH2ADRA1D | |
| SCHEMBL2457538 | 0.80 | NPSR1 (0.42) | GSK3BNPSR1CA12CA9KDM4E | |
| SCHEMBL6152233 | 0.74 | HPRT1 (0.45) | GSK3BKDM4ESMN1; SMN2TDP1POLB | |
| SCHEMBL2457833 | 0.74 | CYP1B1 (0.51) | NPSR1KDM4ESMN1; SMN2POLBMAPT | |
| SCHEMBL8737445 | 0.73 | CASP3 (0.65) | NPSR1CA12CA9ADRA1DADRA1A | |
| SCHEMBL29820192 | 0.73 | CASP3 (0.65) | NPSR1CA12CA9ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1253151-B1 | Pyrromethene metal complex and light emitting device composition and light emitting devices using the same | TORAY INDUSTRIES (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-6805978-B2 | COMPLEX CONTAINING DIKETOPYRROLO(3,4-C)PYRROLE COMPOUND | TORAY INDUSTRIES, INC. (JP) | 2004-10-19 | — | — | US | disclosed |
| US-20030082406-A1 | Complex containing diketopyrrolo(3,4-c)pyrrole compound | TORAY INDUSTRIES, INC. (JP) | 2003-05-01 | — | — | US | disclosed |
| EP-1253151-A1 | Pyrromethene metal complex and light emitting device composition and light emitting devices using the same | TORAY INDUSTRIES, INC. (JP) | 2002-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030082406-A1 | Complex containing diketopyrrolo(3,4-c)pyrrole compound | PPOX, CPNE4, TP53RK | GSK3B 3956/4885CLTC 694/4885NPSR1 3242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.