Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | GOT1 | P17174 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31605465 | 0.80 | — | — | |
| SCHEMBL30075114 | 0.80 | — | — | |
| SCHEMBL1479726 | 0.80 | — | — | |
| SCHEMBL28293 | 0.80 | — | — | |
| SCHEMBL28279241 | 0.78 | P2RX7 (0.57) | P2RX7CES1AHRTBXA2RCYP1A2 | |
| SCHEMBL22288333 | 0.78 | P2RX7 (0.57) | P2RX7CES1AHRTBXA2RCYP1A2 | |
| SCHEMBL15956532 | 0.78 | P2RX7 (0.57) | P2RX7CES1AHRTBXA2RCYP1A2 | |
| Hydrochloric Acid SCHEMBL11797023 | 0.78 | P2RX7 (0.57) | P2RX7CES1AHRTBXA2RCYP1A2 | |
| SCHEMBL8977638 | 0.77 | P2RX7 (0.61) | P2RX7CES1AHRGOT1TBXA2R | |
| SCHEMBL6600285 | 0.77 | P2RX7 (0.46) | P2RX7CES1AHRGOT1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718607-B2 | Atypical coupling method for the preparation of 1,2-di(thiophen-2-yl)ethene-1,2-diol compounds via a Cu(II) catalyst | QATAR UNIVERSITY (QA) | 2023-08-08 | — | — | US | disclosed |
| US-11718607-B2 | Atypical coupling method for the preparation of 1,2-di(thiophen-2-yl)ethene-1,2-diol compounds via a Cu(II) catalyst | QATAR UNIVERSITY (QA) | 2023-08-08 | — | — | US | disclosed |
| US-20220204487-A1 | ATYPICAL COUPLING METHOD FOR THE PREPARATION OF 1,2-DI(THIOPHEN-2-YL)ETHENE-1,2-DIOL COMPOUNDS VIA A CU(II) CATALYST | QATAR UNIVERSITY (QA) | 2022-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718607-B2 | Atypical coupling method for the preparation of 1,2-di(thiophen-2-yl)ethene-1,2-diol compounds via a Cu(II) catalyst | AP2A2, AP2A1, DNM2 | P2RX7 4258/4885CES1 2704/4885AHR 1452/4885 |
| US-20220204487-A1 | ATYPICAL COUPLING METHOD FOR THE PREPARATION OF 1,2-DI(THIOPHEN-2-YL)ETHENE-1,2-DIOL COMPOUNDS VIA A CU(II) CATALYST | AP2A2, AP2A1, DNM2 | P2RX7 4258/4885CES1 2704/4885AHR 1452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.