Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10720943 | 0.86 | PHGDH (0.81) | PHGDHSMN1; SMN2KMT2AHPGDKDM4E | |
| SCHEMBL24783903 | 0.84 | HPGD (0.68) | SMN1; SMN2KMT2AMEN1HPGDKDM4E | |
| SCHEMBL2455541 | 0.83 | HPGD (0.71) | KMT2AMEN1HPGDKDM4EALDH1A1 | |
| SCHEMBL3451002 | 0.81 | L3MBTL3 (0.51) | KMT2AHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL1376416 | 0.81 | GPR183 (0.53) | SMN1; SMN2GAAHPGDKDM4EALDH1A1 | |
| SCHEMBL1017455 | 0.81 | PHGDH (0.69) | PHGDHSMN1; SMN2KMT2ATP53HPGD | |
| SCHEMBL12871 | 0.81 | PHGDH (0.69) | PHGDHSMN1; SMN2KMT2AHPGDKDM4E | |
| SCHEMBL28296651 | 0.80 | HPGD (0.86) | PHGDHSMN1; SMN2KMT2AGAAHPGD | |
| SCHEMBL1374701 | 0.80 | SIGMAR1 (0.62) | HPGDALDH1A1MAPT | |
| SCHEMBL21460055 | 0.80 | PHGDH (0.62) | PHGDHSMN1; SMN2KMT2AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104723717-A | Computer-to-plate flexible plate and production method thereof | LUCKY HUAGUANG GRAPHICS CO LTD | 2015-06-24 | — | — | CN | claimed |
| CN-119504653-A | Carboxylic acid amidation method | 国网安徽省电力有限公司电力科学研究院 | 2025-02-25 | — | — | CN | disclosed |
| WO-2020261294-A1 | NOVEL APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS | MANKIND PHARMA LTD. (IN) | 2020-12-30 | — | — | WO | disclosed |
| CN-104953034-B | Degradable base board for flexible optoelectronic part and preparation method thereof | 电子科技大学 | 2018-03-13 | — | — | CN | disclosed |
| CN-104723717-B | A kind of flexographic plate of CTP and preparation method thereof | 乐凯华光印刷科技有限公司 | 2017-08-25 | — | — | CN | disclosed |
| CN-103594628-B | A kind of organic thin film solar cell and preparation method thereof | UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA (CN) | 2016-05-04 | — | — | CN | disclosed |
| CN-103579504-B | A kind of organic thin film solar cell and preparation method thereof | UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA (CN) | 2016-01-13 | — | — | CN | disclosed |
| CN-103579502-B | A kind of organic field effect tube and preparation method thereof | UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA (CN) | 2015-12-09 | — | — | CN | disclosed |
| CN-103560207-B | A kind of organic thin film solar cell and preparation method thereof | UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA (CN) | 2015-12-09 | — | — | CN | disclosed |
| CN-103594624-B | A kind of organic field effect tube and preparation method thereof | UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA (CN) | 2015-12-09 | — | — | CN | disclosed |
| CN-101465408-A | Substrate for flexible organic optoelectronic device and preparation method thereof | UNIV ELECTRONIC SCIENCE & TECH (CN) | 2009-06-24 | — | — | CN | disclosed |
| CN-101465409-A | Substrate for flexible organic optoelectronic device and preparation method thereof | UNIV ELECTRONIC SCIENCE & TECH (CN) | 2009-06-24 | — | — | CN | disclosed |
| CN-101436644-A | Substrate for flexible organic optoelectronic device and preparation method thereof | UNIV ELECTRONIC SCIENCE & TECH (CN) | 2009-05-20 | — | — | CN | disclosed |
| CN-101425560-A | Substrate for flexible organic optoelectric device and preparation thereof | UNIV ELECTRONIC SCIENCE & TECH (CN) | 2009-05-06 | — | — | CN | disclosed |
| US-6784295-B2 | CARRIED OUT IN THE PRESENCE OF AN INORGANIC BASE OR ORGANIC NITROGEN BASE AND A PALLADIUM COMPLEX CATALYST CONTAINING SECONDARY MONOPHOSPHINES WITH ALIPHATIC, BRANCHED OR CYCLIC SUBSTITUENTS AS LIGANDS | SOLVIAS AG (CH) | 2004-08-31 | — | — | US | disclosed |
| US-20030181688-A1 | Coupling of nucleophiles, vinyl compounds or CO with water, alcohols or amines to organic compounds | INDOLESE ADRIANO (CH) | 2003-09-25 | — | — | US | disclosed |
| EP-1132361-B1 | Coupling of nucleophiles, vinyl compounds or CO with water, alcohols or amines to organic compounds | SOLVIAS AG (CH) | 2003-05-14 | — | — | EP | disclosed |
| US-6548684-B2 | Using monophosphine palladium complex catalyst | SOLVIAS AG (SE) | 2003-04-15 | — | — | US | disclosed |
| US-20010037042-A1 | Coupling of nucleophiles, vinyl compounds or CO with water, alcohols or amines to organic compounds | SOLVIAS AG (CH) | 2001-11-01 | — | — | US | disclosed |
| EP-1132361-A1 | Coupling of nucleophiles, vinyl compounds or CO with water, alcohols or amines to organic compounds | Solvias AG (CH) | 2001-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010037042-A1 | Coupling of nucleophiles, vinyl compounds or CO with water, alcohols or amines to organic compounds | ADH1C, ALKBH3, PNMT | PHGDH 2050/4885SMN1; SMN2 2522/4885KMT2A 976/4885 |
| US-20030181688-A1 | Coupling of nucleophiles, vinyl compounds or CO with water, alcohols or amines to organic compounds | ADH1C, ALKBH3, PNMT | PHGDH 2050/4885SMN1; SMN2 2522/4885KMT2A 976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.