SCHEMBL2458397

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2584398	0.83	POLB (0.43)	—
	SCHEMBL2581807	0.79	CHRM1 (0.45)	PTGS2CLK1RAB9AGFERPPARD
	SCHEMBL2578644	0.77	ESR1 (0.42)	PTGS2CLK1RAB9AGFER
	SCHEMBL12160478	0.77	ESR1 (0.38)	PTGS2CLK1RAB9AGFERPTGDR2
	SCHEMBL2462928	0.76	PDE5A (0.41)	CLK1PDE5A
	SCHEMBL2586348	0.75	ESR1 (0.37)	PTGS2CLK1RAB9AGFER
	SCHEMBL7530216	0.74	PTGS2 (0.44)	PTGS2RAB9AGFERPTGDR2
	SCHEMBL2588104	0.72	FFAR1 (0.40)	PTGS2PPARD
	Hydrochloric Acid SCHEMBL13560349	0.70	CHRM1 (0.41)	PTGS2CLK1RAB9AGFERPTGDR2
	SCHEMBL2458294	0.70	CHRM1 (0.43)	PTGS2CLK1RAB9AGFERPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.