Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24588293 | 0.81 | PGK1 (0.40) | CRHR1HTTPGK1NOS3NOS1 | |
| SCHEMBL6652151 | 0.78 | PIK3CA (0.39) | KMT2AALDH1A1HSD17B10MEN1LMNA | |
| SCHEMBL25388165 | 0.76 | ALDH1A1 (0.40) | KMT2AALDH1A1MEN1CYP1A2MAPT | |
| SCHEMBL30586323 | 0.76 | ALDH1A1 (0.40) | KMT2AALDH1A1MEN1CYP1A2MAPT | |
| SCHEMBL28878645 | 0.76 | MAPT (0.36) | ALDH1A1HSD17B10LMNACYP1A2CYP3A4 | |
| SCHEMBL31247578 | 0.75 | MEN1 (0.40) | KMT2AMEN1PIK3CAMTORNPC1 | |
| SCHEMBL24587298 | 0.74 | NOS3 (0.37) | CRHR1KMT2AALDH1A1HSD17B10MEN1 | |
| SCHEMBL31421660 | 0.74 | NOS3 (0.37) | CRHR1KMT2AALDH1A1HSD17B10MEN1 | |
| SCHEMBL9229440 | 0.69 | MAPT (0.40) | KMT2AALDH1A1MEN1LMNACYP1A2 | |
| SCHEMBL24588117 | 0.69 | LRRK2 (0.41) | KMT2AMEN1LMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022135430-A1 | HETEROARYL COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2022-06-30 | — | — | WO | disclosed |