Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6652151 | 0.78 | PIK3CA (0.39) | MAPTKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL13940610 | 0.77 | KMT2A (0.46) | MAPTKDM4ETBK1ALDH1A1HSD17B10 | |
| SCHEMBL24587409 | 0.76 | CRHR1 (0.35) | MAPTKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL15426468 | 0.75 | MAPT (0.37) | MAPTKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL15577521 | 0.74 | ALDH1A1 (0.39) | ALDH1A1CLK4HTTCCR1CCR5 | |
| SCHEMBL22916642 | 0.73 | PLAU (0.42) | MAPTALDH1A1HSD17B10NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL28381933 | 0.73 | MAPT (0.36) | MAPTKDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL3716987 | 0.73 | MAPK1 (0.49) | MAPTKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL24588117 | 0.73 | LRRK2 (0.41) | LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2655524 | 0.72 | MAPT (0.39) | MAPTALDH1A1IGF1RCCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151540-A | Polyheterocyclic compounds as METTL3 inhibitors | 风暴治疗有限公司 | 2022-10-04 | — | — | CN | disclosed |