Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18819874 | 0.79 | TRPA1 (0.35) | GAABLMSMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL28878645 | 0.78 | MAPT (0.36) | ALDH1A1MAPTKDM4EGAATDP1 | |
| SCHEMBL24587409 | 0.78 | CRHR1 (0.35) | PIK3CAMTORALDH1A1MAPTMEN1 | |
| SCHEMBL2957518 | 0.75 | ALDH1A1 (0.42) | ALDH1A1MAPTMEN1KMT2ATHRB | |
| SCHEMBL22043524 | 0.74 | PDGFRB (0.44) | MEN1KMT2AGAABLMSMN1; SMN2 | |
| SCHEMBL2265758 | 0.74 | NOS3 (0.45) | PIK3CAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3929194 | 0.74 | ALDH1A1 (0.41) | PIK3CAMTORALDH1A1MAPTMEN1 | |
| SCHEMBL24554013 | 0.73 | NOS3 (0.37) | KMT2ANOS3NOS1NOS2LMNA | |
| SCHEMBL9952855 | 0.72 | IDO1 (0.35) | — | |
| SCHEMBL3927303 | 0.72 | PIK3CA (0.49) | PIK3CAMTORALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239818-B1 | ENZYMATIC DYE | HENKEL KGAA (DE) | 2004-06-09 | — | — | EP | disclosed |