Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.45 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.45 |
| ▸ | SMAD2 | Q15796 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 7/20 | 0.45 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2457010 | 0.88 | CYP11B1 (0.47) | CYP11B1CYP11B2IDO1ASIC3POLB | |
| SCHEMBL31214345 | 0.77 | DYRK1A (0.72) | RIPK1DYRK1ATGFBR1BMPR1ASMAD2 | |
| SCHEMBL2457852 | 0.76 | PFKFB3 (0.55) | RIPK1DYRK1ATGFBR1BMPR1ASMAD2 | |
| SCHEMBL2458543 | 0.75 | CYP11B1 (0.47) | CYP11B1CYP11B2IDO1ASIC3POLB | |
| SCHEMBL30718016 | 0.73 | CYP11B1 (0.53) | CYP11B1CYP11B2TGFBR1IDO1ASIC3 | |
| SCHEMBL2460153 | 0.73 | RIPK2 (0.55) | RIPK1DYRK1APOLBHPGDSCYP3A4 | |
| SCHEMBL2457537 | 0.73 | CYP11B1 (0.57) | CYP11B1CYP11B2IDO1ASIC3POLB | |
| SCHEMBL991449 | 0.72 | QPCT (0.58) | CYP11B1CYP11B2IDO1ASIC3POLB | |
| SCHEMBL2457484 | 0.72 | DYRK1A (0.49) | RIPK1DYRK1ATGFBR1BMPR1ASMAD2 | |
| SCHEMBL2465324 | 0.71 | CYP11B1 (0.58) | DYRK1ACYP11B1CYP11B2IDO1ASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237633-A1 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237633-A1 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | HGF, HDGF, MET | RIPK1 3658/4885DYRK1A 4134/4885CYP11B1 2027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.